POST OPERATIVE PAIN, ACUTE
Clinical trials for POST OPERATIVE PAIN, ACUTE explained in plain language.
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New combo pill aims to ease teen surgery pain
Symptom relief Not yet recruitingThis study tests a new painkiller called Combogesic 325, which combines ibuprofen and acetaminophen, in 180 teens aged 12 to 17 recovering from orthopedic surgery. Participants receive either 2 or 3 tablets of Combogesic or plain acetaminophen every 6 hours for 24 hours. The goal…
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: PHASE3 • Sponsor: AFT Pharmaceuticals, Ltd. • Aim: Symptom relief
Last updated Jul 02, 2026 03:00 UTC
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Finding the right dose: nerve block study aims to ease Post-Surgery pain
Symptom relief Not yet recruitingThis study compares three different volumes of a local anesthetic nerve block (SPSIP block) in 90 adults undergoing modified radical mastectomy. The goal is to see which volume best reduces pain and the need for additional painkillers like tramadol. Researchers will also map whic…
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: NA • Sponsor: Cumhuriyet University • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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New study tests simple trick to stop pain after nerve blocks wear off
Symptom relief Not yet recruitingThis study tests whether giving scheduled morphine alongside patient-controlled pain relief can prevent the intense 'rebound pain' that often occurs when a nerve block wears off after orthopaedic surgery. About 100 adults having arm or leg surgery will be randomly assigned to rec…
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: NA • Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Symptom relief
Last updated Jun 27, 2026 14:02 UTC
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New study tests simple trick to stop pain after nerve block wears off
Symptom relief Not yet recruitingThis study tests whether giving scheduled morphine doses alongside on-demand pain relief can prevent the severe 'rebound pain' that often occurs when a nerve block wears off after orthopedic surgery. One hundred adults having arm or leg surgery will be randomly assigned to receiv…
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: NA • Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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New study aims to cut Post-Surgery pain by sucking out trapped gas
Symptom relief Not yet recruitingThis study compares three ways to remove carbon dioxide gas left in the belly after laparoscopic surgery to see which one reduces pain the most. 150 adults having non-emergency laparoscopic surgery will be randomly assigned to active gas removal, breathing maneuvers, or no extra …
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: NA • Sponsor: Henry Ford Health System • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Root canal relief? study tests weaker bleach for less pain
Symptom relief Not yet recruitingThis study compares two strengths of sodium hypochlorite (a disinfectant used during root canals) to see which causes less pain afterward. 116 adults needing a root canal will be randomly assigned to receive either a 2.5% or 5.25% solution. Pain levels will be measured at 6, 12, …
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: NA • Sponsor: College of Physicians and Surgeons Pakistan • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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Could a single dose of ketamine during heart surgery stop Long-Term pain?
Symptom relief Not yet recruitingThis study will test whether giving a single dose of ketamine during open-heart surgery can reduce chronic pain that often lingers for months after the operation. Researchers will compare 100 adults who receive either ketamine or a placebo during surgery, then track their pain le…
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: NA • Sponsor: Bursa City Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:00 UTC
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Root canal showdown: which sealer hurts less?
Symptom relief Not yet recruitingThis study aims to find out which of two root canal sealers causes less pain after treatment. Sixty adults with tooth nerve inflammation will have root canals and then rate their pain over two days. The goal is to improve patient comfort and recovery.
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: PHASE2, PHASE3 • Sponsor: Jaweria Gul Keyani • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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New study tests simpler nerve block for hip surgery pain
Symptom relief Not yet recruitingThis study compares two ways to manage pain after a second hip replacement. One group gets a PENG block (a targeted injection around the hip joint), while the other gets a combination of blocks around the thigh and hip. Both use the same numbing medicine. The goal is to see which…
Matched conditions: POST OPERATIVE PAIN, ACUTE
Phase: NA • Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC