Could a single dose of ketamine during heart surgery stop Long-Term pain?
NCT ID NCT07490457
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test whether giving a single dose of ketamine during open-heart surgery can reduce chronic pain that often lingers for months after the operation. Researchers will compare 100 adults who receive either ketamine or a placebo during surgery, then track their pain levels and painkiller use for up to 6 months. If successful, this simple addition to anesthesia could improve recovery and reduce reliance on opioids.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ketamine
- What this could lead to
- If it works, this could point toward a simple way to prevent long-term pain after open-heart surgery and reduce the need for strong painkillers.
- What could go wrong
- This is a small, early-stage trial (100 people) that hasn't started yet. The results may not apply to all heart surgery patients, and ketamine can cause side effects like confusion or hallucinations.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Bursa City Hospital,
Bursa, nilüfer, Turkey (Türkiye)
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