New combo pill aims to ease teen surgery pain without opioids
NCT ID NCT07225140
First seen Nov 06, 2025 · Last updated May 15, 2026 · Updated 27 times
Summary
This study tests whether a new combination painkiller (Combogesic 325, which mixes ibuprofen and acetaminophen) works better than acetaminophen alone for teens aged 12 to 17 recovering from orthopedic surgery. About 180 teens will be randomly assigned to one of three groups, taking either 2 or 3 tablets of the combo or 2 tablets of acetaminophen every 6 hours. Pain levels will be tracked for 24 hours, and extra opioids can be given if needed.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Nemours Children's Health
Orlando, Florida, 32827, United States
Contact Phone: •••-•••-••••
Conditions
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