Could a simple infusion ease pain after appendix surgery?

NCT ID NCT07678385

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This trial investigates whether giving lidocaine through a vein during laparoscopic appendectomy can reduce pain and speed up recovery after surgery. The study includes adults aged 18 to 45 who are scheduled for this procedure. Participants receive either lidocaine or a placebo (saline) infusion, and researchers measure pain levels, opioid use, nausea, bowel function recovery, and hospital stay length.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

lidocaine

What this could lead to

If it works, this could provide a simple, low-cost way to reduce pain and opioid use after laparoscopic appendectomy.

What could go wrong

This is a single-center trial with a moderate number of participants. Lidocaine may not significantly improve pain or recovery, and there is a small risk of side effects like dizziness or heart rhythm changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Universitario de Caracas

    Caracas, Miranda, 1040, Venezuela