Could a simple infusion ease pain after appendix surgery?

NCT ID NCT07678385

Completed Symptom relief Sponsor: Hospital Universitario de Caracas Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This trial investigates whether giving lidocaine through a vein during laparoscopic appendectomy can reduce pain and speed up recovery after surgery. The study includes adults aged 18 to 45 who are scheduled for this procedure. Participants receive either lidocaine or a placebo (saline) infusion, and researchers measure pain levels, opioid use, nausea, bowel function recovery, and hospital stay length.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: lidocaine
What this could lead to: If it works, this could provide a simple, low-cost way to reduce pain and opioid use after laparoscopic appendectomy.
What could go wrong: This is a single-center trial with a moderate number of participants. Lidocaine may not significantly improve pain or recovery, and there is a small risk of side effects like dizziness or heart rhythm changes.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LAPAROSCOPIC APPENDECTOMY POST OPERATIVE PAIN, ACUTE

Contacts and locations

Locations

Hospital Universitario de Caracas

Caracas, Miranda, 1040, Venezuela

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