PANCREATITIS

This study tests whether giving a short course of two medicines (hydrocortisone and octreotide) plus using a patch made from the patient's own tissue during surgery can lower the chance of serious complications after a Whipple procedure. The Whipple is a complex operation to remo…

This study tests whether giving a short course of intravenous hydrocortisone, an anti-inflammatory steroid, to adults with severe acute pancreatitis can reduce inflammation and improve recovery. About 86 participants in intensive care will receive either the drug or a placebo. Th…

This study looks at whether a urine dipstick test can quickly detect pancreatitis after pancreas removal surgery. About 50 adults having elective pancreatectomy will provide urine samples before, during, and after surgery. The goal is to see if this simple test works as well as s…

This study tests if applying nitroglycerin directly to the bile duct opening during an ERCP procedure can prevent pancreatitis, a common and serious complication. Researchers will enroll 440 adults who need ERCP to remove bile duct stones. Half will receive the nitroglycerin spra…

This study compares two drugs, indomethacin and diclofenac, given as suppositories before an ERCP procedure to prevent pancreatitis, a common and serious complication. About 4,050 adults aged 18-90 who have not had prior bile duct surgery will be randomly assigned to receive one …

This study tests whether rinsing the bile duct opening with cold water at the end of an ERCP procedure, in addition to standard medication, can lower the chance of developing pancreatitis—the most common serious complication after ERCP. About 950 adults with a natural bile duct o…

This study tests an internet-delivered pain self-management program for adults with chronic pancreatitis. The goal is to reduce pain severity and its interference with daily activities like sleep, mood, and work. Researchers will enroll 280 participants to see if this psychologic…

This study tests Scrambler Therapy, a non-invasive device that sends gentle electrical signals through the skin to retrain how the brain feels pain. It is for adults with chronic pancreatitis whose belly pain has not improved with standard treatments. About 40 participants will r…

This study tests a mobile app that gives personalized tips and insights based on blood sugar, exercise, mood, and sleep patterns. The goal is to help 60 adults aged 30-65 with type 1 diabetes or similar conditions exercise more often and safely. All participation is remote, so yo…

This study creates a registry of people with pancreatic diseases or a high risk for pancreatic cancer, such as those with a family history or certain genetic mutations. Researchers will collect medical information and blood samples to study how these conditions develop over time.…

This study follows 250 adults undergoing pancreatic surgery for cancer, cysts, or pancreatitis. Researchers will track changes in quality of life, symptoms, and emotional well-being for up to two years. The goal is to help doctors and patients have better conversations about what…

This study follows over 2,300 people with and without chronic pancreatitis to learn what causes the disease and how it progresses. Researchers collect health information and symptoms over time to find better ways to treat or prevent it. Participants do not receive any experimenta…

This study is a large registry that collects data on how a blood-filtering device called CytoSorb is used in real-world intensive care settings. It will include up to 3,000 critically ill patients with conditions like septic shock, severe lung injury, or liver failure. The goal i…

This study aims to create a simple, less invasive test to find pancreatic cancer at an early stage and monitor how well treatment is working. Researchers will study 700 people with pancreatic cancer, pancreatitis, or pancreatic cysts. The goal is to identify biological markers in…