Cold water trick may stop pancreatitis after common procedure
NCT ID NCT07330284
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether rinsing the bile duct opening with cold water at the end of an ERCP procedure, on top of standard medication, can reduce the risk of pancreatitis—the most common major complication after ERCP. About 950 adults with a natural papilla (the bile duct opening) will be randomly assigned to receive either cold or room-temperature water irrigation. The main goal is to see if cold water lowers the rate of post-ERCP pancreatitis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cold water irrigation
What this could lead to
If it works, this simple, low-cost addition could become a standard step during ERCP to prevent pancreatitis, the most common serious complication.
What could go wrong
This is an early-stage trial with no phase designation, so results are uncertain. The benefit may be small or not apply to all patients, and cold water could cause discomfort or other minor side effects.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Kansas Cancer Center
RECRUITINGKansas City, Kansas, 66160, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••