PALLIATIVE CARE

This study tests whether adding a special care program (GRACE) to regular annual check-ups can improve health and reduce hospital stays for older adults with multiple health issues. About 6,000 people aged 65 and older who speak English or Spanish will take part. The program incl…

This study explores whether virtual reality (VR) can help people receiving palliative care—and their companions—achieve personal goals like relaxation or bucket-list experiences. Up to 12 patients will take part in up to 3 VR sessions at a hospice in England. Researchers will tra…

This study is testing a new supportive care program called POISE for people with advanced non-small cell lung cancer. The program includes four visits with a specially trained palliative care clinician to help patients cope with uncertainty and manage their cancer journey. Resear…

This small pilot study will test whether medicinal cannabis can help ease symptoms like pain, muscle spasms, and gut problems in 10 children (ages 6 months to 21 years) who are receiving palliative care for non-cancer conditions. The main goal is to see if families find the treat…

This study tests a mobile app called ICUconnect that helps older adults in the ICU and their families report their needs and get better support. The app aims to improve care and reduce emotional distress. About 350 patient-family pairs will take part across four hospitals.

This study is testing whether a structured care plan, based on symptoms reported by patients, can improve quality of life for adults with advanced cancer. About 120 participants will either receive standard palliative care or a personalized plan that triggers specific support bas…

This study tests whether a nasal spray containing midazolam can quickly reduce sudden anxiety in adults receiving palliative care. About 36 participants will receive either a low dose, a higher dose, or a placebo spray. Researchers will measure anxiety levels before and 30 minute…

This study aims to reduce suffering for adults in the intensive care unit (ICU) by providing palliative care consultations. Researchers will track how long patients stay in the ICU and whether these consultations help them leave sooner. The study involves 2,040 participants acros…

This study tests whether moderate to high doses of LSD can reduce anxiety, depression, and pain in people with advanced, life-limiting illnesses. Sixty participants with a life expectancy of 12 weeks to 2 years will receive either two doses of LSD or a very low dose as a placebo.…

This study tests whether giving testosterone injections every 15 days can improve quality of life in men with low testosterone who are receiving best supportive care and have no further treatment options. The study will enroll 20 men and track changes in daily living activities a…

This study tests an experimental drug called resiniferatoxin (RTX), made from a cactus-like plant, to treat severe pain in people with advanced cancer. RTX works by destroying pain-signaling nerves. The trial involves 45 adults whose pain is not controlled by standard treatments.…

This study looks at how people with advanced cancer feel about stopping medicines they may no longer need. Many patients take multiple drugs, which can cause side effects and lower quality of life. Researchers will interview about 325 patients and use questionnaires to understand…

This study tests a training program called ABCs that teaches healthcare providers how to have better conversations with patients facing serious illnesses. The program includes online lessons and virtual workshops. Researchers want to see if this training helps clinicians feel mor…

This study looks at how palliative and supportive care might help people with inflammatory arthritis (like rheumatoid arthritis) manage pain, fatigue, and emotional challenges. Researchers will interview patients and survey doctors to understand current gaps in care. The goal is …

This study looks at what helps or hinders creating care plans for vulnerable patients in medicalized residential care who need palliative care. Researchers will interview staff and patients to understand the organizational and human factors involved. About 100 adults in Alsace, F…

This study looks at how cancer patients in palliative care feel about stopping medications that are not for their cancer. Researchers will give patients a brochure and video explaining their medicines and then ask them questions to see if their views change. The goal is to learn …

This study surveys about 150 palliative care patients and healthcare professionals to understand oral health problems like dry mouth and infections, and how well dental care is integrated into palliative medicine. The goal is to identify gaps in knowledge and practice so that den…