PAIN, ACUTE
Clinical trials for PAIN, ACUTE explained in plain language.
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ER pain relief breakthrough: breathing morphine instead of shots
Symptom relief CompletedThis study tested whether inhaling morphine through a mask works as well as getting it through an IV drip for treating severe pain in emergency rooms. Researchers compared the two methods in 226 adults with intense pain to see which provided faster, more effective relief. The goa…
Matched conditions: PAIN, ACUTE
Phase: PHASE3 • Sponsor: University Hospital, Rouen • Aim: Symptom relief
Last updated Apr 02, 2026 00:41 UTC
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Hand massage study tests natural relief after heart procedure
Symptom relief CompletedThis study tested whether two types of hand massage—reflexology or a standard technique—could help patients feel better after a coronary angiography procedure. Researchers worked with 70 adults who had just undergone this heart artery imaging test, measuring their pain, anxiety, …
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated Mar 31, 2026 12:12 UTC
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Mind over pain: can talk therapy ease recovery after a broken bone?
Symptom relief CompletedThis study tested whether a type of talk therapy called cognitive behavioral therapy (CBT) could help reduce long-term pain after surgery for a broken arm or leg. Over 1,000 adults who had surgery for a fracture received either CBT or standard care. The goal was to see if changin…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: McMaster University • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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Scientists test VR as a pain distraction tool
Symptom relief CompletedThis small study tested whether using immersive virtual reality could reduce how much pain people feel from brief heat sensations. Researchers compared pain ratings when participants experienced the heat with and without using a VR headset. The study involved 24 University of Was…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: University of Washington • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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Targeted shot could ease agony of broken ribs, cut opioid need
Symptom relief CompletedThis study tested if a targeted ultrasound-guided nerve block could help emergency room patients with broken ribs. It compared the block to standard pain care to see if it improved patients' ability to breathe deeply and cough while reducing their need for opioid painkillers. The…
Matched conditions: PAIN, ACUTE
Phase: EARLY_PHASE1 • Sponsor: Rhode Island Hospital • Aim: Symptom relief
Last updated Mar 30, 2026 14:34 UTC
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A simple grasp: could a Baby's reflex be the key to easing medical pain?
Symptom relief CompletedThis study tested whether stimulating a premature baby's natural grasp reflex could reduce their pain and improve comfort during routine PICC line care. Researchers worked with 32 preterm infants, gently triggering this reflex while nurses performed the necessary care. The goal w…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: Ataturk University • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Common pain pill put to the test: is ibuprofen safe after major surgery?
Symptom relief CompletedThis large study tested whether taking ibuprofen for eight days after hip or knee replacement surgery is safe. Nearly 3,000 patients were randomly given either ibuprofen or a placebo pill to see which group had fewer serious complications. The goal was to find the best balance be…
Matched conditions: PAIN, ACUTE
Phase: PHASE4 • Sponsor: Naestved Hospital • Aim: Symptom relief
Last updated Mar 27, 2026 12:39 UTC
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Can knowing It's fake make pain feel real? emergency room tests honest placebos
Symptom relief CompletedThis study explored whether giving patients sugar pills they know are placebos is a practical way to help manage sudden, unexplained pain in the emergency department. Researchers compared the 'honest placebo' against standard ibuprofen treatment in 57 adults to see if the approac…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: Bruno Minotti • Aim: Symptom relief
Last updated Mar 25, 2026 14:08 UTC
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Virtual reality goggles tested as new tool to ease Kids' surgery pain
Symptom relief CompletedThis study tested whether a virtual reality (VR) program could help children and teenagers manage pain after surgery. Researchers first developed a training and treatment plan using the VR technology. Then, they tested if using this plan was practical and if it helped reduce pati…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: Vanessa Olbrecht • Aim: Symptom relief
Last updated Mar 23, 2026 15:29 UTC
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Nerve blocks battle for best pain relief after surgery
Symptom relief CompletedThis study compared two different nerve-block techniques to see which provides better pain relief after abdominal surgery. Researchers tested the Quadratus Lumborum block against the Erector Spinal block in 100 patients undergoing various abdominal procedures. The goal was to det…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: Jagiellonian University • Aim: Symptom relief
Last updated Mar 23, 2026 15:19 UTC
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Texting away the pain: app helps new moms breastfeed longer
Symptom relief CompletedThis study tested a smartphone-based support program to help new mothers manage common breast and nipple pain during breastfeeding. Over 200 women were randomly assigned to receive either the educational program with nurse texting support or general postpartum information. The go…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: University of Connecticut • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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Could breathing hydrogen gas ease your surgery pain?
Symptom relief CompletedThis small study tested whether inhaling hydrogen gas around the time of surgery could help control pain and reduce inflammation afterward. It involved 37 adults having a specific back surgery for a herniated disc. Researchers measured patients' pain levels and blood markers to s…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: Fu Jen Catholic University Hospital • Aim: Symptom relief
Last updated Mar 11, 2026 14:53 UTC
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Can a pinch of pain erase what you just learned? study tests memory in aging
Knowledge-focused CompletedThis study aimed to understand how temporary pain affects a person's ability to learn and remember new walking patterns, especially in older adults. Researchers tested 61 healthy young and older adults, using mild electrical stimulation to create brief pain during a walking task.…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: University of Delaware • Aim: Knowledge-focused
Last updated Apr 02, 2026 00:41 UTC
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Does your weight affect your pain after back surgery?
Knowledge-focused CompletedThis study looked at whether a person's body weight affects how much pain they feel after surgery for a slipped disc in the lower back. Researchers studied 75 adults who had this surgery and received a specific type of pain-blocking injection. The goal was to understand if higher…
Matched conditions: PAIN, ACUTE
Sponsor: Atatürk Chest Diseases and Chest Surgery Training and Research Hospital • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Zapping the ear to tune the body? scientists probe inner sensations
Knowledge-focused CompletedThis study explored whether a gentle electrical stimulation to the ear (transauricular vagal nerve stimulation) can change how healthy people sense signals from inside their bodies, like pain, their heartbeat, and temperature. Fifty healthy adults participated in experiments wher…
Matched conditions: PAIN, ACUTE
Phase: NA • Sponsor: Aalborg University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:34 UTC
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First-of-its-Kind study sheds light on hidden pain in liver disease patients
Knowledge-focused CompletedThis study aimed to find out how common pain is for people with liver cirrhosis who are in the hospital. Researchers asked 30 hospitalized patients about their pain, its location, intensity, and how it affects their sleep and quality of life. The goal was to gather basic informat…
Matched conditions: PAIN, ACUTE
Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists probe why pain spikes when numbing wears off
Knowledge-focused CompletedThis study aims to understand 'rebound pain,' a severe pain spike some people feel when a numbing nerve block from surgery wears off. Researchers tested 40 healthy volunteers by giving them a numbing injection in the arm and then measuring their pain sensitivity as it wore off. T…
Matched conditions: PAIN, ACUTE
Phase: PHASE1 • Sponsor: Brigham and Women's Hospital • Aim: Knowledge-focused
Last updated Mar 17, 2026 13:09 UTC