Slow-Drip ketamine may ease pain with fewer weird side effects

NCT ID NCT05518877

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving a low dose of ketamine over 30 minutes instead of 15 minutes could reduce side effects like dizziness or hallucinations while still controlling acute pain. 55 adults with severe pain in the emergency department took part. The goal was to find a better balance between pain relief and unwanted effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

ketamine

What this could lead to

If successful, this could lead to a safer way to give ketamine for acute pain in the emergency room, with fewer side effects like dizziness or hallucinations.

What could go wrong

This is a small, early-phase trial with only 55 participants. The results may not apply to all patients or settings, and side effects may still occur.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain dissociative disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Summa Health System

    Akron, Ohio, 44304, United States