Love hormone put to the test as painkiller

NCT ID NCT07053774

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 4 times

Summary

This completed phase 2 trial tested whether oxytocin, given as a nasal spray or through an IV, can reduce pain from heat in healthy adults. Twenty-four participants rated their pain on a 0-10 scale after skin heating. The study also looked at whether age, weight, or sex affect how well oxytocin works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

oxytocin

What this could lead to

If it works, this could point toward a new way to manage acute pain using oxytocin.

What could go wrong

This is a small, early-phase trial in healthy volunteers, not patients with chronic pain. The pain is lab-induced, so results may not apply to real-world pain conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist

    Winston-Salem, North Carolina, 27157, United States