Love hormone put to the test as painkiller

NCT ID NCT07053774

First seen Jun 25, 2026 · Last updated Jul 01, 2026 · Updated 4 times

Summary

This completed phase 2 trial tested whether oxytocin, given as a nasal spray or through an IV, can reduce pain from heat in healthy adults. Twenty-four participants rated their pain on a 0-10 scale after skin heating. The study also looked at whether age, weight, or sex affect how well oxytocin works.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
oxytocin
What this could lead to
If it works, this could point toward a new way to manage acute pain using oxytocin.
What could go wrong
This is a small, early-phase trial in healthy volunteers, not patients with chronic pain. The pain is lab-induced, so results may not apply to real-world pain conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Acute Pain agnosia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Atrium Health Wake Forest Baptist

    Winston-Salem, North Carolina, 27157, United States

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Other studies related to the condition(s) this trial covers.