OVERWEIGHT OR OBESITY

This study tested an experimental injection called ZT002 in 303 adults who are overweight or have obesity. The goal was to see how much weight people lost after 24 weeks of treatment compared to a placebo. The study also looked at how many people lost at least 5%, 10%, or 15% of …

This study tested a virtual health program for African immigrants aged 25-75 who are uninsured and have at least two risk factors like high blood pressure, prediabetes, or obesity. Participants used Bluetooth scales and blood pressure monitors to track their health over six month…

This study tested whether retatrutide, a drug originally developed for weight loss, can help protect kidney function in people who are overweight or obese and have chronic kidney disease, with or without type 2 diabetes. About 146 participants took part in this 31-week trial. The…

This study tested whether a probiotic called Akkermansia muciniphila Akk11 can help overweight or obese adults improve their metabolism and gut health. 110 participants took either the probiotic or a placebo daily. Researchers measured changes in appetite-related hormones and gut…

This study gave 580 Native American adults and children in the Osage Nation a weekly box of fresh produce along with healthy recipes and cooking materials. The goal was to see if this program could improve diet, lower blood pressure, and reduce health risks like obesity and food …

This early-stage study tested the safety and tolerability of a new injectable drug called ZT002 in 28 adults who were overweight or obese. Participants received either the drug or a placebo, and researchers monitored for side effects and how the drug moved through the body. The g…

This early-stage study tested a new medicine called HRS-4729 in 102 healthy adults who were overweight or had obesity. The main goal was to check if the drug is safe and how the body processes it. Participants received either the drug or a placebo as a shot under the skin, and re…

This study looked at whether helping people sleep longer or on a more regular schedule could improve their metabolic health and lower their risk for diabetes and obesity. Researchers studied 18 overweight adults who typically slept less than 7 hours a night. Over 24 days, they tr…

This early-stage study tested a new drug called CT-996 in 94 adults who were overweight or had type 2 diabetes. The main goal was to check if the drug is safe and how the body processes it. Researchers gave single or multiple doses and watched for side effects. This is a first st…

This study tested an experimental daily pill called TERN-601 for weight loss in 167 adults with overweight or obesity. Participants took the pill or a placebo for 12 weeks to see how much weight they lost and if it was safe. The goal is to find a convenient oral treatment to help…

This study tested a once-daily pill called orforglipron against insulin glargine in about 2,700 adults with type 2 diabetes who were also overweight or obese and had higher heart risk. The goal was to see if the pill is safe and effective at controlling blood sugar and preventing…

This study tested a program called eMOMS that combines breastfeeding support with a diabetes prevention plan for women who were overweight or obese before pregnancy. The program was delivered by a health coach through a mobile app. Researchers wanted to see if it could help with …

This study tested an online guided self-help program for teenagers aged 12 to 17 who struggle with binge eating and are overweight. Over four months, participants completed weekly online sessions. The goal was to see if the program is practical and helpful for reducing binge eati…

This study tested two online treatments for teenagers who have bulimia nervosa (binge eating and purging) and are also overweight. The goal was to see if these treatments are practical and acceptable. 25 teens took part, and researchers measured changes in binge eating and purgin…

This study tested a special cooling pillow pad called Moona to see if it could help African American adults with overweight or obesity sleep better. 18 people took part. The goal was to measure changes in sleep quality and related health markers like blood sugar control. The stud…

This early-stage study tested the drug AMG 133 in 57 adults with overweight or obesity. The main goal was to see how the drug affects stomach emptying, measured by how the body processes acetaminophen. The study also checked for side effects and changes in appetite and food intak…

This study tested a new computer algorithm that uses data from wearable devices (like fitness trackers and continuous glucose monitors) to predict a person's real-time risk of developing prediabetes. Researchers collected health and lifestyle information from 77 overweight or mil…