OVERACTIVE BLADDER

This study tests if mirabegron, a drug used for overactive bladder, can also help treat dry age-related macular degeneration (AMD). Researchers will compare mirabegron to another bladder drug in 312 people aged 50-80 with both conditions. Participants take the drug daily for 12 m…

This study looks at whether three proteins found in urine—RhoA, NGF, and BDNF—can help doctors diagnose and track overactive bladder in children aged 4 to 18 who also have low vitamin D. Researchers will measure these proteins using a lab test and compare them to symptom scores. …

This study tests whether adding gabapentin to the standard drug solifenacin works better than solifenacin alone for women with overactive bladder. About 60 women will receive either the combination or the single drug, and researchers will track symptom changes and side effects ov…

This study tests whether taking probiotics twice a day for 12 weeks can reduce how often people with overactive bladder (OAB) and anxiety need to urinate, and whether it can also lower their anxiety. All participants will also learn bladder training techniques. The study will com…

This study tests whether a mix of nitrous oxide (laughing gas) and oxygen can reduce pain during in-office bladder Botox injections for overactive bladder. About 96 adult women will receive either the gas plus standard numbing medicine or a fake mask plus standard care. Participa…

This study looks at different ways to treat overactive bladder symptoms in people with Parkinson's disease. Researchers want to see if combining behavioral therapy and medication helps those who don't improve with just one treatment. About 146 adults with Parkinson's and signific…

This study is translating and testing a questionnaire called USIQ for Turkish-speaking women with overactive bladder. The goal is to ensure the tool accurately measures urgency severity and its impact on daily life. About 130 women aged 18-65 will complete the questionnaire along…

This study follows 500 Beijing residents aged 60 and older to see how urinary function (like bladder and kidney health) relates to multiple health problems such as high blood pressure, diabetes, and heart disease. Participants will have regular check-ups, blood and urine tests, a…

This study looks at whether people with overactive bladder can be monitored at home after receiving botulinum toxin injections, instead of going to the hospital. About 112 adults will be randomly assigned to either home or hospital follow-up. The main goal is to see if home monit…

This study looks at how two different weight loss methods—medication (GLP-1 drugs) and surgery—change pelvic floor symptoms like bladder control, urgency, and vaginal prolapse in women. About 200 women aged 18-89 with a BMI of 30 or higher will be followed. The goal is to help do…