OVERACTIVE BLADDER

This study is testing a small implanted device called eCoin that stimulates a nerve in the leg to help control sudden urine leaks (urgency urinary incontinence). About 200 adults with overactive bladder will get the implant and be followed for up to 2 years. The goal is to see if…

This study tests a device that uses mild electrical pulses to calm bladder nerves in men with overactive bladder. It aims to reduce sudden urges and frequent urination, and improve quality of life. The study involves 150 men and will track safety and effectiveness for up to one y…

This study looks at how two different types of bladder medication affect thinking skills in women aged 60 and older who have sudden, strong urges to urinate. Participants will be randomly assigned to take one of two drugs or a placebo for 6 months. The goal is to see which option…

This study tests a new ultrasound method to measure bladder function without invasive procedures. Researchers at Mayo Clinic will compare the new technique to standard tests in adults with bladder issues or enlarged prostate. The goal is to see if this painless approach can accur…

This study tests whether a chair that uses electromagnetic energy (Emsella) can help people with overactive bladder. Participants get two treatments per week for four weeks. The goal is to see if it reduces urgency, frequency, and leakage better than a fake treatment.

This study looks at women with urgent bladder leaks or frequent urination who are getting a nerve-stimulating device. Normally, a week-long trial predicts if the device will work, but this research tests if a 3-day trial is just as good. The goal is to make the process faster and…

This study looks at whether adding high-dose vitamin D to standard care helps children with overactive bladder (wet type) reach their goal of zero leakage. About 180 children aged 5 and older with low vitamin D levels will receive either standard treatment alone or standard treat…

This study tests whether a small, at-home nerve stimulation device can help women in rural areas manage overactive bladder symptoms. About 38 women will use the device daily and report changes in bladder control and quality of life. The goal is to find a simple, drug-free option …

This study is testing a new device called Tensi+ that uses mild electrical pulses to help people with overactive bladder. Researchers will track 500 adults for one year to see if the device improves symptoms like sudden urges to urinate. The goal is to learn how well it works and…

This study tests a non-invasive brain stimulation technique called rTMS to improve overactive bladder symptoms in women with multiple sclerosis. About 29 participants will receive either real or sham treatment over 10 sessions. The goal is to see if targeting specific brain areas…

This study tests a device that uses radiofrequency energy inside the vagina to treat overactive bladder in women. It includes 202 women aged 22 to 80 who have had symptoms for at least 6 months. Half will get the real treatment and half a sham (fake) treatment to see if the devic…

This study looks at whether using different X-ray settings during a procedure for overactive bladder can lower radiation exposure. About 44 adults will take part. The goal is to see if the new settings are safer while still helping doctors place the device correctly.

This study tests whether adding Botox injections into the bladder during standard prostate surgery (HoLEP) can better relieve overactive bladder symptoms like sudden urges and leaking. About 66 men aged 18-89 with these symptoms will be randomly assigned to get either Botox or a …

This study looks at whether yoga can improve overactive bladder symptoms in children aged 8 to 18. Participants attend a weekly yoga session for 6 weeks. Researchers will track symptom changes using questionnaires and urine tests. The goal is to find a gentle, non-drug option for…

This study tests whether a daily cranberry extract pill can change the bacteria in the bladder to reduce sudden urges and frequent bathroom trips in women who do not have leakage. Researchers will compare bacteria samples and symptom scores before and after 12 weeks of treatment.…

This study looks at whether women with overactive bladder can remove a temporary nerve testing lead at home instead of coming to the doctor's office. The lead is used to see if a permanent nerve device might help their symptoms. Researchers want to know if at-home removal is just…

This study tests a special sock called the ZIDA Control Sock that gives mild electrical pulses near the ankle to help people with overactive bladder who still have leaks despite taking medicine. About 20 adults will use the sock at home once a week for 12 weeks while staying on t…

This study looks at how bladder filling sensations are linked to overactive bladder (OAB) severity in people with multiple sclerosis (MS). Researchers will measure bladder sensitivity during a standard test called urodynamics. The goal is to better understand bladder symptoms in …

This study aims to understand how electrical stimulation of the sacral nerve helps people with overactive bladder. Researchers will test two different ways to set the stimulation and see which one works better. Fifteen adults who already qualify for a sacral nerve implant will pa…

This study aims to collect electrical signals from the body in people with overactive bladder, fecal incontinence, or urinary retention. Researchers will gather these signals at several points during the therapy evaluation period. The goal is to better understand how the body res…

This study aims to find out how often sexual dysfunction occurs in women with relapsing-remitting multiple sclerosis and how it connects to fatigue, depression, anxiety, overactive bladder, and thinking problems. Researchers will use questionnaires and tests to measure these fact…