Laughing gas may ease pain of bladder botox shots

NCT ID NCT07387315

First seen Feb 04, 2026 · Last updated May 15, 2026 · Updated 9 times

Summary

This study tests whether a mix of nitrous oxide (laughing gas) and oxygen can reduce pain during in-office bladder Botox injections for overactive bladder. About 96 adult women will either receive the gas or a placebo mask alongside standard numbing medication. Researchers will measure pain, anxiety, and satisfaction to see if the gas helps.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cincinnati Urogynecology Associates

    Cincinnati, Ohio, 45220, United States

  • Trihealth (Good Samaritan Hospital, Bethesda North Hospital)

    Cincinnati, Ohio, 45220, United States

Conditions

Explore the condition pages connected to this study.