Laughing gas may ease pain of bladder botox shots

NCT ID NCT07387315

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a mix of nitrous oxide (laughing gas) and oxygen can reduce pain during in-office bladder Botox injections for overactive bladder. About 96 adult women will receive either the gas plus standard numbing medicine or a sham mask plus standard care. Participants will rate their pain, anxiety, and satisfaction after the procedure.

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Conditions

The condition(s) this trial relates to.

agnosia overactive bladder Pain Pelvic Floor Disorders Urinary Bladder, Neurogenic Urinary Incontinence Urinary Incontinence, Urge

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Urogynecology Associates

    Cincinnati, Ohio, 45220, United States

  • Trihealth (Good Samaritan Hospital, Bethesda North Hospital)

    Cincinnati, Ohio, 45220, United States

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