OVARIAN CARCINOMA

This large, late-stage trial is testing whether adding a special heated chemotherapy wash to standard surgery helps people with advanced ovarian cancer stay cancer-free for longer. The study compares two groups: one receives the heated chemo during their tumor-removal surgery, an…

This is a first-in-human study to find a safe dose and see how the body processes a new oral drug called ATV-1601. It is being tested in adults with advanced solid tumors, including certain breast cancers, that have a specific genetic change called an AKT1 E17K mutation. The main…

This study is testing a drug called sacituzumab govitecan in people with ovarian, fallopian tube, or primary peritoneal cancer that has returned and is resistant to standard platinum-based chemotherapy. The goal is to see if this targeted drug can shrink tumors and control the di…

This large national trial is testing whether choosing cancer drugs based on the specific genetic changes found in a patient's tumor is more effective than standard approaches. It is for adults with advanced solid tumors, lymphoma, or multiple myeloma that have progressed after at…

This study is testing a combination of two oral drugs, olaparib and cediranib, to see if they can help control recurrent ovarian, fallopian tube, or primary peritoneal cancer. It is for women whose cancer has returned after previous treatment. The main goals are to see if the dru…

This early safety study aims to find the right dose and understand the side effects of a new drug combination for people with advanced solid tumors who also have liver or kidney problems. It tests adding a pill called veliparib to standard chemotherapy drugs. The main goal is to …

This study is testing whether a newer type of combined PET/MR scan is better than the standard CECT scan at finding ovarian cancer tumors and predicting if they can be fully removed by surgery. About 21 patients with known or suspected ovarian cancer will receive both scans befor…

This study is testing different ways to help people at high risk for cancer or cancer survivors become more active and eat healthier foods. Researchers are comparing methods like weekly phone calls, emails, daily text messages, and online forums to see which combinations work bes…

This study compares three different approaches to prevent ovarian cancer in women who carry BRCA gene mutations. Participants choose between regular cancer screening, immediate removal of ovaries and fallopian tubes, or a new two-step surgery that removes tubes first and delays o…

This study is testing whether eating more magnesium-rich foods can prevent low magnesium levels in the blood, a common side effect of carboplatin chemotherapy for ovarian cancer. Researchers are working with 26 patients to see if this dietary approach is practical and effective. …

This study aims to understand how often and when muscle loss occurs in women with advanced ovarian cancer who cannot have immediate surgery. Researchers will measure muscle mass using CT scans before and during chemotherapy in 25 patients. The goal is to gather information that c…

This study is testing a web-based education tool called HOPE-Genomics to see if it helps cancer patients better understand their personal genetic test results and general cancer genomics. Researchers are comparing the tool's effectiveness against standard education methods in abo…