New study tests two-step surgery to delay menopause while cutting ovarian cancer risk

NCT ID NCT01907789

First seen Nov 01, 2025 · Last updated May 29, 2026 · Updated 30 times

Summary

This study looks at three approaches to prevent ovarian cancer in women with BRCA1 or BRCA2 gene mutations: regular screening, removing both fallopian tubes and ovaries at once, or removing only the fallopian tubes first and the ovaries later. The two-step surgery aims to delay menopause and its side effects. About 80 premenopausal women aged 30-47 are taking part to see how many complete the delayed ovary removal and whether the fallopian tube removal alone lowers cancer risk.

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Contacts and locations

Locations

  • NorthShore University Health System

    Evanston, Illinois, 60201, United States

  • University of Texas MD Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.