OVARIAN CARCINOMA

This early-stage study aimed to find the safest dose of two drugs, sapanisertib and ziv-aflibercept, when given together to patients with advanced solid tumors that had stopped responding to standard treatments. The main goal was to understand the side effects and determine the h…

This early-stage study tested whether combining two drugs—trabectedin and durvalumab—is safe and shows promise for treating advanced soft-tissue sarcoma and ovarian cancer. The trial involved 40 patients whose cancers had progressed despite previous treatments. Researchers aimed …

This study tested whether adding an experimental drug called TJ004309 to an existing immunotherapy (atezolizumab) could help control advanced cancers that have stopped responding to standard treatments. It involved 25 patients with specific types of advanced solid tumors, includi…

This study tested whether adding an experimental drug called MK-4830 to standard immunotherapy and chemotherapy could better shrink tumors before surgery in people with high-grade ovarian cancer. Researchers measured tumor DNA in the blood to see if the new combination was more e…

This early-stage trial tested a personalized cancer vaccine called TG4050 in patients with ovarian, fallopian tube, or peritoneal cancer who were in remission after initial treatment. The main goal was to check if the vaccine was safe and well-tolerated. Researchers also looked f…

This study aimed to understand how weight loss affects muscle energy production in women with ovarian or endometrial cancer. Researchers compared 70 women with cancer-related weight loss to women having surgery for non-cancerous conditions. They analyzed muscle and tissue samples…

This study tested whether a simple saliva sample, collected at home, could be used to track cytomegalovirus (CMV) infection in people being treated for ovarian cancer. Researchers compared virus levels in saliva to standard blood tests in 49 participants. The goal was to see if r…