Scientists probe muscle mysteries in cancer weight loss

NCT ID NCT03027479

Completed Knowledge-focused Sponsor: University Hospital, Tours Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study looked at how muscle energy use differs in women with ovarian or endometrial cancer who are losing weight, depending on their body mass index (BMI). Researchers took blood samples, muscle biopsies, and fat tissue from 70 women during surgery. The goal was to understand the biological changes behind cancer-related weight loss, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors understand why some cancer patients lose muscle and weight, potentially pointing to future ways to prevent or treat this wasting.
What could go wrong: This is an observational study with only 70 participants, so results may not apply to all patients. It does not test any treatment, so no direct benefit is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endometrial carcinoma endometrium neoplasm Obesity ovarian cancer ovarian carcinoma Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ENDOMETRIAL CARCINOMA OVARIAN CARCINOMA WEIGHT LOSS

Contacts and locations

Locations

Gynecology Department, University Teaching Hospital, Tours

Tours, 37044, France

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