OSTEOSARCOMA
Clinical trials for OSTEOSARCOMA explained in plain language.
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New hope for young sarcoma patients after standard treatments fail
Disease control CompletedThis study tested whether combining two chemotherapy drugs, nab-paclitaxel and gemcitabine, could help control cancer in teenagers and young adults whose bone or soft tissue sarcoma had returned or stopped responding to standard treatments. The main goals were to see if the combi…
Matched conditions: OSTEOSARCOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New hope for Tough-to-Treat bone cancer?
Disease control CompletedThis study tested the safety and early effectiveness of a new drug called azenosertib (ZN-c3) when given with an existing chemotherapy drug, gemcitabine. It involved 31 adults and teenagers (12+) whose osteosarcoma (a type of bone cancer) had come back or stopped responding to pr…
Matched conditions: OSTEOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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New hope for tough bone cancer: immune therapy trial for kids and young adults
Disease control CompletedThis study tested whether a drug called avelumab could help control a rare and aggressive bone cancer called osteosarcoma when it comes back after standard treatment. It involved 19 patients aged 12 to 50 whose cancer had returned or worsened. The main goals were to see if the dr…
Matched conditions: OSTEOSARCOMA
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Targeted attack: new method aims to starve and poison bone tumors
Disease control CompletedThis study tested a new way to deliver cancer drugs directly to bone tumors (osteosarcoma) before surgery. Researchers gave a two-drug combination through a tiny tube placed in an artery feeding the tumor, along with standard chemotherapy given through a vein. The goal was to see…
Matched conditions: OSTEOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Shanghai 6th People's Hospital • Aim: Disease control
Last updated Mar 18, 2026 14:40 UTC
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Radiation-Free scans for kids with cancer: a safer way to track tumors?
Knowledge-focused CompletedThis study tested whether a special type of MRI scan, which uses no radiation, could work as well as standard scans that do use radiation for children with bone and soft tissue cancers (sarcomas). Researchers wanted to see if this safer method could correctly identify where the c…
Matched conditions: OSTEOSARCOMA
Phase: NA • Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Scientists hunt for genetic clues in rare bone cancer
Knowledge-focused CompletedThis study aimed to understand the genetic causes of osteosarcoma, a rare bone cancer. Researchers collected health information, saliva, blood, and other samples from 362 patients and their family members. The goal was to compare genes between people with and without the disease …
Matched conditions: OSTEOSARCOMA
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Computers scour old medical records for clues to beat rare bone cancers
Knowledge-focused CompletedThis study used computer programs to analyze old medical records from 700 patients with two rare and aggressive bone cancers, osteosarcoma and Ewing's sarcoma. The goal was to find patterns in the data that could help predict which patients might have better or worse survival out…
Matched conditions: OSTEOSARCOMA
Sponsor: University of Milano Bicocca • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:29 UTC
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Scientists test DNA blueprint method to find better treatments for kids with tough cancers
Knowledge-focused CompletedThis study tested whether doctors could quickly analyze the genetic makeup of a child's tumor and use that information to choose a personalized treatment plan. It involved 186 children and young adults (up to age 21) whose cancers had returned or did not respond to standard treat…
Matched conditions: OSTEOSARCOMA
Phase: NA • Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated Mar 18, 2026 14:41 UTC