OSTEOSARCOMA
Clinical trials for OSTEOSARCOMA explained in plain language.
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New hope for young bone cancer patients: immune drug tested in relapse
Disease control CompletedThis study tested a drug called avelumab in 19 children and young adults (ages 12 to 49) whose osteosarcoma (a type of bone cancer) had come back or was not responding to standard treatments. The goal was to see if avelumab could shrink tumors or stop the cancer from growing for …
Matched conditions: OSTEOSARCOMA
Phase: PHASE2 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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New Artery-Delivered cocktail shows promise against bone cancer
Disease control CompletedThis study tested a new way to treat osteosarcoma, a type of bone cancer, in 10 patients. Doctors gave two drugs—cisplatin and Endostar—directly into the artery that feeds the tumor, along with standard chemotherapy through a vein. The goal was to see if this approach was safe an…
Matched conditions: OSTEOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: Shanghai 6th People's Hospital • Aim: Disease control
Last updated May 16, 2026 23:47 UTC
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New drug combo shows promise for tough sarcomas in young patients
Disease control CompletedThis study tested whether a combination of two chemotherapy drugs, nab-paclitaxel and gemcitabine, can stop or slow tumor growth in teenagers and young adults (ages 3 to 30) whose sarcoma (a type of bone or soft tissue cancer) had returned or was not responding to standard treatm…
Matched conditions: OSTEOSARCOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 16, 2026 23:36 UTC
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New hope for hard-to-treat bone cancer? early trial tests drug combo
Disease control CompletedThis early-stage study tested a new drug (ZN-c3) combined with standard chemotherapy (gemcitabine) in 31 people aged 12 and older with osteosarcoma that had returned or stopped responding to treatment. The main goals were to check safety and see if the combination could slow or s…
Matched conditions: OSTEOSARCOMA
Phase: PHASE1 • Sponsor: K-Group, Beta, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc • Aim: Disease control
Last updated May 16, 2026 23:36 UTC
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Could a Radiation-Free scan replace X-Rays for kids with cancer?
Knowledge-focused CompletedThis study looked at whether a special type of MRI (DW-MRI) that uses no radiation can work as well as standard scans like CT and PET-CT for children with bone or soft-tissue sarcomas. About 98 children participated to see if the MRI could accurately detect tumors and show how we…
Matched conditions: OSTEOSARCOMA
Phase: NA • Sponsor: St. Jude Children's Research Hospital • Aim: Knowledge-focused
Last updated May 16, 2026 23:47 UTC
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Tumor DNA map could personalize care for kids with relapsed cancer
Knowledge-focused CompletedThis study looked at whether it's possible to use a child's tumor DNA to choose their next treatment. 186 children with cancers that came back or didn't respond to standard therapy had their tumors analyzed. The goal was to see if this approach could be done quickly enough to gui…
Matched conditions: OSTEOSARCOMA
Phase: NA • Sponsor: Giselle Sholler • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC
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AI sifts through 700 bone cancer records to uncover survival clues
Knowledge-focused CompletedThis study looked at the medical records of 700 people diagnosed with osteosarcoma or Ewing's sarcoma between 2003 and 2012. Researchers used computer programs and machine learning to find patterns in the data, especially around survival. No new treatments were given or tested.
Matched conditions: OSTEOSARCOMA
Sponsor: University of Milano Bicocca • Aim: Knowledge-focused
Last updated May 11, 2026 20:37 UTC
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New biobank aims to unlock genetic secrets of rare bone cancer
Knowledge-focused CompletedThis study created a registry and biobank for people with osteosarcoma, a rare bone cancer, and their family members. Researchers collected genetic samples from 362 participants to compare genes of those with and without the disease. The goal was to learn if certain genes are lin…
Matched conditions: OSTEOSARCOMA
Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Apr 26, 2026 19:36 UTC