ORAL CAVITY SQUAMOUS CELL CARCINOMA
Clinical trials for ORAL CAVITY SQUAMOUS CELL CARCINOMA explained in plain language.
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Could a common food additive help fight oral cancer?
Disease control Recruiting nowThis study is for people with oral cavity squamous cell carcinoma (a type of mouth cancer) who are scheduled for surgery. Researchers want to see if taking nisin, a natural food preservative, is safe and can change the bacteria in the mouth in a helpful way. About 40 participants…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated May 17, 2026 04:13 UTC
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New weekly combo may offer hope for head and neck cancer patients who can't take standard chemo
Disease control Recruiting nowThis study tests a weekly treatment of two chemotherapy drugs (carboplatin and paclitaxel) plus an immunotherapy drug (pembrolizumab) in 32 people with advanced head and neck cancer that has spread. It is for patients who cannot take the standard drug 5-fluorouracil. The goal is …
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Could less radiation be safer? new trial aims to shrink treatment zones without raising cancer return risk
Disease control Recruiting nowThis study tests whether giving radiation only to high-risk areas after surgery for head and neck cancer can lower side effects without increasing the chance of cancer coming back. About 50 adults with certain types of head and neck cancer will receive a personalized radiation pl…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Olgun Elicin • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Immunotherapy duo shows promise in advanced oral cancer trial
Disease control Recruiting nowThis study tests whether adding two immunotherapy drugs (tiragolumab and atezolizumab) before and after standard surgery and chemoradiation can improve outcomes for people with newly diagnosed, advanced oral cavity squamous cell carcinoma that has a specific marker (PD-L1 CPS pos…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New study tests if smaller neck surgery can spare shoulder function in oral cancer patients
Disease control Recruiting nowThis study compares two types of surgery for early-stage oral cavity cancer: a newer, less invasive approach called sentinel lymph node biopsy that removes only a few key lymph nodes, versus the standard elective neck dissection that removes many lymph nodes. The goal is to see i…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated May 14, 2026 12:03 UTC
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Could a Two-Drug punch before surgery beat head and neck cancer?
Disease control Recruiting nowThis study tests whether adding an experimental drug (CDX-1140) to a standard immunotherapy (cemiplimab) before surgery can shrink advanced head and neck cancers more than the immunotherapy alone. About 44 people with stage III-IV head and neck cancer will receive either the comb…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 12, 2026 13:40 UTC
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New drug aims to ease painful mouth sores for head and neck cancer patients
Symptom relief Recruiting nowThis study tests whether adding BMX-001 to standard care can reduce severe mouth sores caused by chemoradiation in head and neck cancer patients. About 98 participants will receive either BMX-001 or a placebo alongside their usual treatment. The goal is to improve quality of life…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: NRG Oncology • Aim: Symptom relief
Last updated May 17, 2026 04:28 UTC
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Researchers hunt for clues to improve cancer treatment in patients who Can't take standard chemo
Knowledge-focused Recruiting nowThis study looks at 250 patients with head and neck cancers who cannot take the standard chemotherapy drug cisplatin. Researchers will analyze tumor tissue, saliva, stool, and blood samples to find biological markers that predict how well treatment with chemoradiotherapy and doce…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Sponsor: University of Erlangen-Nürnberg Medical School • Aim: Knowledge-focused
Last updated May 17, 2026 04:17 UTC
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Remote hearing tests could save cancer Patients' hearing
Knowledge-focused Recruiting nowThis study looks at whether offering hearing tests close to home or remotely can help more head and neck cancer patients get their hearing checked during and after treatment. Many patients on cisplatin chemotherapy or radiation may lose hearing, but traveling to the clinic for te…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Emory University • Aim: Knowledge-focused
Last updated May 11, 2026 20:38 UTC