ORAL CAVITY SQUAMOUS CELL CARCINOMA
Clinical trials for ORAL CAVITY SQUAMOUS CELL CARCINOMA explained in plain language.
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New pastille could change head and neck cancer treatment
Disease control Not yet recruitingThis large Phase 3 trial is testing a new drug called APG-157, given as a pastille that dissolves in the mouth, for people with advanced head and neck cancer. The study will see if adding APG-157 before and after standard treatments (surgery or chemoradiation) helps keep the canc…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Aveta Biomics, Inc. • Aim: Disease control
Last updated Jul 02, 2026 06:00 UTC
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New drug cocktail aims to shrink oral tumors before surgery
Disease control Not yet recruitingThis phase 2 trial tests a combination of two drugs, XL-092 and pembrolizumab (Keytruda), given before surgery to people with a type of oral cancer that is HPV-negative and can be removed. The goal is to see if the drugs can shrink or eliminate the tumor before the operation. Abo…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: UNC Lineberger Comprehensive Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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New radiation combo aims to shrink oral tumors before surgery
Disease control Not yet recruitingThis early-phase study tests a new type of radiation (lattice radiotherapy) given with chemotherapy and immunotherapy before surgery for oral cavity cancer. About 30 adults with advanced but removable tumors will receive different radiation doses to find the safest level. The goa…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: NYU Langone Health • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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AI could spot mouth cancer early from a simple photo
Diagnosis Not yet recruitingThis study will collect thousands of photos of mouth lesions from patients seen over 50 years at a French hospital. Experts will review each photo to confirm the diagnosis. Researchers will then use these images and patient data to train an AI system to automatically identify can…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 12:07 UTC
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Acupuncture timing may be key to preventing dry mouth in head and neck cancer patients
Symptom relief Not yet recruitingThis trial compares early versus delayed acupuncture to reduce dry mouth caused by chemoradiation in head and neck cancer patients. Participants receive acupuncture either during chemoradiation or after, and their dry mouth symptoms are tracked for a year. The goal is to find the…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: National University Hospital, Singapore • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Dye technique could spare neck surgery for head and neck cancer patients
Knowledge-focused Not yet recruitingThis study tests whether injecting two dyes around the tumor and into cancerous lymph nodes can help surgeons spot hidden cancer spread in head and neck cancer. Twenty adults with oral cavity or head and neck skin cancer will receive the dyes before surgery. The goal is to see if…
Matched conditions: ORAL CAVITY SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Centre Hospitalier Universitaire Vaudois • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:05 UTC