Could a food preservative help fight oral cancer?
NCT ID NCT06097468
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether nisin, a natural preservative found in some foods, can safely change the bacteria in the mouths of people with oral cavity squamous cell carcinoma. About 40 patients will take nisin before and after their standard surgery. The goal is to find a safe dose and see if it affects the mouth's microbiome.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Nisin (a natural food preservative)
What this could lead to
If it works, this could point toward a simple, low-cost way to improve outcomes for oral cancer patients by altering mouth bacteria.
What could go wrong
This is a very early, small trial (40 people) testing safety and dosing. It may not show any benefit, and nisin might cause side effects or fail to change bacteria meaningfully.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, San Francisco
RECRUITINGSan Francisco, California, 94143, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact