NEOPLASM METASTASIS

This early-phase study tested a new drug called MRX-2843 in 42 adults with advanced or metastatic solid tumors that had not responded to prior treatments. The main goal was to check the drug's safety and find the best dose. Researchers monitored side effects and how the drug move…

This early-phase trial tested a new drug called LY3039478 in 247 people with advanced or metastatic cancer, including lymphoma. The main goal was to find a safe dose and see how the drug affects the body. Researchers also looked for signs that the drug might shrink tumors.

This study tested a new immunotherapy drug called ezabenlimab (BI 754091) combined with other cancer medicines in 211 adults with advanced solid tumors that had spread. The goal was to see if the combinations could shrink or eliminate tumors. Participants received treatment until…

This study tested a new way to give chemotherapy for pancreatic cancer that spread only to the liver, after the first treatment stopped working. Doctors delivered two drugs directly into the liver artery, followed by more chemo or pills. The goal was to see if this approach could…

This study looked at whether liver cancer spreads differently in men and women. Researchers analyzed data from over 19,000 patients and used machine learning to create separate prediction tools for each gender. The goal was to better understand which factors predict cancer spread…

This study explored whether intestinal polyps release tumor cells or other substances into the blood that could signal early cancer spread. Researchers compared blood samples from 120 people with and without polyps. The goal was to find new biomarkers to improve monitoring and gu…

This study observed 500 adults with colorectal cancer that spread to the liver. All were treated with the Emprint Microwave Ablation System, which uses heat to destroy tumors. The goal was to see how well the system controls liver tumors at 12 months and to track any side effects…

This study observed 152 adults with colorectal cancer that had spread mainly to the liver. They were treated with LifePearl microspheres loaded with irinotecan, a chemotherapy drug delivered directly to the liver. The goal was to see how doctors actually use this treatment in pra…

This study looked at how people with advanced cancer decide to talk about and write down their wishes for medical care if their condition gets worse. Researchers offered patients two special conversations about their preferences and tracked who took part. The goal was to learn mo…

This study looked at whether analyzing the DNA of tumors from people with advanced solid cancers could help doctors pick a targeted therapy. Over 500 participants had their tumor samples genetically tested. The goal was to see how often this approach could identify a specific tre…