NEOPLASM METASTASIS

This study tested a new immunotherapy drug called ezabenlimab, given in combination with other cancer medicines, for adults with advanced cancers that had spread. The goal was to see if these combinations could shrink tumors and control the disease in patients who had already tri…

This study tested a two-part treatment for pancreatic cancer that had spread only to the liver after the first standard therapy stopped working. Doctors delivered chemotherapy directly into the liver's blood supply, followed by either more liver-targeted treatment or oral medicat…

This first-in-human study tested a new oral medication called MRX-2843 in adults with advanced solid tumors that had returned or stopped responding to standard treatments. The main goals were to find the highest safe dose and understand how the drug moves through the body. Resear…

This was the first human study of an experimental cancer drug called LY3039478. Researchers tested it in 247 patients with advanced or metastatic cancer to find the highest dose that could be given safely. The study also looked for early signs that the drug might help shrink tumo…

This study observed how well a microwave heating treatment works for patients whose colorectal cancer has spread to the liver. It followed 500 patients across Europe who received this standard procedure to see if it controlled their liver tumors for at least a year. The goal was …

This study aimed to discover if a simple blood test could detect early signs of cancer spread from intestinal polyps. Researchers compared blood samples from 120 people with polyps to those without, looking for specific cells and proteins. The goal is to find better ways to monit…

This study analyzed information from 19,019 liver cancer patients to understand if men and women have different risks of their cancer spreading. Researchers used national cancer database records and advanced computer programs to create separate prediction tools for each gender. T…

This study aimed to understand if patients with advanced cancer would engage in structured discussions to plan their future care if their illness worsened. Researchers offered 71 patients two interviews to assess their wishes and begin these sensitive conversations. The goal was …