NAFLD
Clinical trials for NAFLD explained in plain language.
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Plant power: natural supplement shows promise for fatty liver
Disease control CompletedThis study tested whether a natural plant compound called phytosterol can help people with non-alcoholic fatty liver disease (NAFLD). Twenty-seven adults took the supplement for three months to see if it improved liver enzymes, cholesterol, insulin levels, and inflammation. The g…
Matched conditions: NAFLD
Phase: NA • Sponsor: University of Jordan • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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Could this pill lower cholesterol in fatty liver patients?
Disease control CompletedThis study tested an experimental drug called elobixibat in 47 adults with nonalcoholic fatty liver disease (NAFLD) or its more serious form, NASH. Participants received either the drug or a placebo for 16 weeks. The main goal was to see if elobixibat could lower LDL (bad) choles…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Albireo • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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Can a tailored mediterranean diet and exercise reverse fatty liver?
Disease control CompletedThis study tested two versions of a low-calorie Mediterranean diet, each with different carb and fat levels, combined with moderate aerobic exercise in 36 adults with obesity and fatty liver disease (NAFLD). The goal was to see if one diet plan worked better than the other at red…
Matched conditions: NAFLD
Phase: NA • Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Disease control
Last updated Jun 15, 2026 19:02 UTC
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Drug or diet? new study tests semaglutide against lifestyle changes for PCOS teens
Disease control CompletedThis study looked at 60 teenage girls with PCOS, obesity, and fatty liver disease. Half received the drug semaglutide, and the other half followed a special diet for 12 weeks. The goal was to see which approach better reduced liver fat and improved how the body uses insulin.
Matched conditions: NAFLD
Phase: PHASE2, PHASE3 • Sponsor: University of Colorado, Denver • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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Tomato diet shows promise for fatty liver and gut health
Disease control CompletedThis study looked at whether adding tomatoes to the diet can improve liver health, gut function, and blood sugar in people with non-alcoholic fatty liver disease (NAFLD). 80 adults with NAFLD and a BMI of 30 or less followed a tomato-enriched diet for 6 weeks. Researchers measure…
Matched conditions: NAFLD
Phase: NA • Sponsor: Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis • Aim: Disease control
Last updated Jun 11, 2026 12:09 UTC
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New drug shows promise against fatty liver disease in major trial
Disease control CompletedThis study tested a new medicine called efinopegdutide in 381 adults with non-alcoholic steatohepatitis (NASH), a serious fatty liver disease. The main goal was to see if the drug could reverse liver inflammation without making scarring worse, compared to a placebo. Researchers a…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 10, 2026 13:25 UTC
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Can a hormone pill melt liver fat? small study explores new hope for NAFLD
Disease control CompletedThis pilot study tested a drug called ibutamoren in 12 adults with nonalcoholic fatty liver disease (NAFLD). The goal was to see if it could reduce fat buildup in the liver. Participants took the medication for 6 months, and researchers measured liver fat using a special MRI scan…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 10, 2026 13:24 UTC
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Could a Two-Drug combo reverse fatty liver scarring?
Disease control CompletedThis study tested whether a combination of two drugs, dasatinib and quercetin, can reduce liver scarring in people with non-alcoholic fatty liver disease (NAFLD) and fibrosis. Thirty adults with biopsy-confirmed liver scarring took part in a 21-week randomized, double-blind trial…
Matched conditions: NAFLD
Phase: PHASE1, PHASE2 • Sponsor: Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) • Aim: Disease control
Last updated Jun 08, 2026 13:08 UTC
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New drug shows promise in reducing liver fat in fatty liver disease
Disease control CompletedThis study tested a new drug called DD01 in 67 overweight or obese adults with a type of fatty liver disease (MASLD or MASH). The goal was to see if DD01 could safely reduce liver fat over 48 weeks. Participants were randomly assigned to receive DD01 or a placebo, and researchers…
Matched conditions: NAFLD
Phase: PHASE2 • Sponsor: Neuraly, Inc. • Aim: Disease control
Last updated Jun 08, 2026 13:07 UTC
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New study uses MRI to track fatty liver in diabetic patients
Knowledge-focused CompletedThis study looked at how common and severe fatty liver disease is in people with type 2 diabetes. Researchers used advanced MRI scans to measure liver fat, inflammation, and scarring. 317 patients were checked twice, three years apart, to see how the disease changes over time. Th…
Matched conditions: NAFLD
Sponsor: Linkoeping University • Aim: Knowledge-focused
Last updated Jun 16, 2026 12:49 UTC
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Scientists probe Glucagon's role in liver fat and diabetes
Knowledge-focused CompletedThis study looked at how the hormone glucagon affects the liver's ability to break down amino acids and produce sugar. Researchers compared lean and obese people, some with type 2 diabetes and fatty liver, to see if the liver becomes resistant to glucagon. The goal was to better …
Matched conditions: NAFLD
Phase: PHASE1, PHASE2 • Sponsor: Adrian Vella • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:04 UTC
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Blood tests may replace painful liver biopsies for diabetes patients
Knowledge-focused CompletedThis study looked at whether two blood tests, eLIFT and FibroMeter, can accurately detect liver fibrosis (scarring) in people with type 2 diabetes. Liver fibrosis is common in diabetes and can lead to serious liver problems, but the best way to check for it is a liver biopsy, whi…
Matched conditions: NAFLD
Phase: NA • Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 11, 2026 11:57 UTC
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New study aims to replace painful liver biopsies with simple tests
Knowledge-focused CompletedThis study looked at 1005 people with non-alcoholic fatty liver disease (NAFLD) to find better ways to check liver damage without using a needle biopsy. Researchers tested blood tests and special ultrasound devices to see how well they can spot serious liver scarring. The goal is…
Matched conditions: NAFLD
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:18 UTC
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Liver disease Patients' vaccine response under microscope
Knowledge-focused CompletedThis study looked at how people with chronic liver disease (like hepatitis B, C, or fatty liver) respond to COVID-19 vaccines. About 233 adults had blood tests and answered questions over three visits, each six months apart. The goal was to see if liver disease severity affects v…
Matched conditions: NAFLD
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 03, 2026 12:07 UTC
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Fatty liver disease costs revealed in belgian study
Knowledge-focused CompletedThis study looked at the financial impact of non-alcoholic fatty liver disease (NAFLD) on patients and the healthcare system in Flanders, Belgium. Researchers surveyed 73 adults with NAFLD to measure their medical costs and quality of life. The goal was to understand how much thi…
Matched conditions: NAFLD
Phase: NA • Sponsor: Hasselt University • Aim: Knowledge-focused
Last updated Jun 01, 2026 17:57 UTC
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No more Breath-Holds: new MRI technique could make liver scans easier for kids
Knowledge-focused CompletedThis study tested a new type of MRI that lets children breathe normally during the scan, instead of holding their breath. The goal was to see if it can accurately measure liver fat and stiffness, which helps diagnose fatty liver disease and liver scarring. 135 children aged 6-17 …
Matched conditions: NAFLD
Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 01, 2026 17:56 UTC