MYELODYSPLASTIC SYNDROME
Clinical trials for MYELODYSPLASTIC SYNDROME explained in plain language.
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Experimental combo targets hard-to-treat blood cancers
Disease control TerminatedThis early-stage study tested two drugs, AZD1775 and belinostat, in 20 adults with certain blood cancers (like acute myeloid leukemia) that came back or didn't respond to prior therapy. The main goal was to find the safest dose and check side effects. The study was stopped early,…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 00:47 UTC
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Blood cancer transplant study tests safer GVHD prevention
Disease control TerminatedThis study looked at people with blood cancers receiving a stem cell transplant from an unrelated donor. The goal was to compare two drug combinations (cyclosporine plus sirolimus with either MMF or post-transplant cyclophosphamide) to prevent graft-versus-host disease (GVHD), a …
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated May 17, 2026 00:46 UTC
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Promising combo for tough leukemias hits roadblock: trial ends early
Disease control TerminatedThis study tested a combination of two drugs, venetoclax and decitabine, in 235 people with certain blood cancers (like acute myeloid leukemia and high-risk myelodysplastic syndrome) that either came back or didn't respond to prior treatment, or in older adults who couldn't handl…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 00:32 UTC
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Promising combo for tough blood cancer hits snag: trial halted
Disease control TerminatedThis study tested two drugs, venetoclax and azacitidine, together in people with a serious type of bone marrow cancer called high-risk myelodysplastic syndrome (MDS). The goal was to find the best dose and see if the combo could shrink or control the cancer. The trial included 51…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Blood cancer transplant study seeks best prep regimen
Disease control TerminatedThis study looked at adults with certain blood cancers (like leukemia) who needed a stem cell transplant. It compared two different drug combinations given before the transplant to see which one better prevented the cancer from coming back. The study was stopped early, but the go…
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE3 • Sponsor: Hackensack Meridian Health • Aim: Disease control
Last updated May 11, 2026 20:52 UTC
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Experimental combo for tough leukemia shows promise but study halted early
Disease control TerminatedThis study tested a chemotherapy combination containing cladribine for people whose acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS) had returned or not responded to prior treatment. The goal was to see if the treatment could wipe out signs of the disease …
Matched conditions: MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: Medical College of Wisconsin • Aim: Disease control
Last updated May 06, 2026 16:01 UTC