Blood pressure drug tested to prevent transplant complication

NCT ID NCT02338232

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tested the blood pressure drug telmisartan (Micardis) to prevent acute graft-versus-host disease (GVHD) in people receiving a stem cell transplant for blood cancers. The trial aimed to enroll 60 participants but was terminated early with 32. Researchers tracked severe GVHD cases and side effects like low blood pressure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

telmisartan (Micardis)

What this could lead to

If it worked, telmisartan could offer a new way to prevent GVHD after stem cell transplants, reducing severe complications.

What could go wrong

The trial was terminated early with only 32 participants, so results are limited. Telmisartan may not be effective or could cause side effects like low blood pressure.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia acute myeloid leukemia B-cell chronic lymphocytic leukemia chronic myelogenous leukemia, BCR-ABL1 positive graft versus host disease Hodgkins lymphoma myelodysplastic syndrome myeloproliferative neoplasm non-Hodgkin lymphoma plasma cell myeloma acute graft versus host disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hackensack University Medical Center

    Hackensack, New Jersey, 07601, United States