MOOD DISORDERS
Clinical trials for MOOD DISORDERS explained in plain language.
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New hope: esketamine may match ECT for suicidal ideation
Symptom relief CompletedThis study tested whether esketamine (a nasal spray) works as well as electroconvulsive therapy (ECT) for quickly reducing suicidal thoughts in people with depression or bipolar disorder. 340 adults aged 18-65 with moderate to severe suicidal ideation took part. The goal was to s…
Matched conditions: MOOD DISORDERS
Phase: NA • Sponsor: Capital Medical University • Aim: Symptom relief
Last updated May 17, 2026 08:04 UTC
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Peer power: new program aims to lift student moods
Symptom relief CompletedThis study tested a program called Mood Lifters for college students struggling with depression, anxiety, or stress. The program uses peer-led group meetings to help students feel better without needing expensive one-on-one therapy. 125 undergraduate students took part to see if …
Matched conditions: MOOD DISORDERS
Phase: NA • Sponsor: University of Michigan • Aim: Symptom relief
Last updated May 17, 2026 08:02 UTC
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New therapy uses sleep and daily rhythms to fight suicide risk in young people
Symptom relief CompletedThis study tested a non-drug program called BE-SMART-DR in 65 teens and young adults with bipolar disorder or major depression who had suicidal thoughts or past attempts. The therapy teaches self-guided strategies to regularize sleep and daily routines, aiming to lower short-term…
Matched conditions: MOOD DISORDERS
Phase: NA • Sponsor: Yale University • Aim: Symptom relief
Last updated May 14, 2026 12:03 UTC
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Can fish oil and other natural supplements help kids with mood swings?
Symptom relief CompletedThis study tested two natural supplement combinations—omega-3 fatty acids plus inositol versus N-acetylcysteine (NAC)—to see if they could help children and teens (ages 5-17) with emotional ups and downs. Over 6 weeks, 27 participants took one of the two treatments. The goal was …
Matched conditions: MOOD DISORDERS
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Symptom relief
Last updated May 06, 2026 16:13 UTC
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Gut check: could your stomach bugs be causing your anxiety?
Knowledge-focused CompletedThis study explored whether certain harmful gut bacteria are linked to anxiety, depression, and panic disorders. Researchers analyzed stool samples from 500 adults, including people with these conditions and healthy controls. The goal was to find patterns that could lead to new t…
Matched conditions: MOOD DISORDERS
Sponsor: University of Toronto • Aim: Knowledge-focused
Last updated May 17, 2026 08:04 UTC
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Family ties: unlocking the genetic links between mood disorders and migraines
Knowledge-focused CompletedThis study looked at nearly 2,000 people from the community to understand how depression, anxiety, and migraine are passed down through families. Researchers interviewed family members of all ages and collected health history to find patterns and risk factors. The goal is to use …
Matched conditions: MOOD DISORDERS
Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated May 14, 2026 12:03 UTC
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Can a special video platform help kids engage more in therapy?
Knowledge-focused CompletedThis study looked at whether a virtual therapy platform called Teleo helps children with anxiety or mood disorders stay more engaged in online therapy compared to regular video calls. 41 children took part, and researchers measured engagement using video recordings and caregiver …
Matched conditions: MOOD DISORDERS
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated May 14, 2026 12:01 UTC
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Brain wave test could personalize mental health treatment for veterans
Knowledge-focused CompletedThis study looked at 100 veterans with mental health conditions like schizophrenia, PTSD, anxiety, or mood disorders. The goal was to see if a simple brain wave test (called mismatch negativity) could help choose the best thinking skills training for each person. Researchers meas…
Matched conditions: MOOD DISORDERS
Sponsor: VA Office of Research and Development • Aim: Knowledge-focused
Last updated May 13, 2026 16:02 UTC
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Fruit and veggie breakfast boosts Kids' brainpower, study finds
Knowledge-focused CompletedThis study looked at whether giving 7-11-year-old children in Shanghai a daily breakfast with fruits and vegetables could improve their thinking, mood, and attention. Over 250 kids took part, eating the extra produce for 12 weeks. Researchers measured changes in cognitive skills,…
Matched conditions: MOOD DISORDERS
Phase: NA • Sponsor: Fudan University • Aim: Knowledge-focused
Last updated May 01, 2026 15:58 UTC