MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Clinical trials for MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE explained in plain language.
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Supercharged immune cells take aim at myeloma
Disease control Recruiting nowThis early-stage trial tests whether specially trained immune cells can safely target and attack multiple myeloma, as well as its early forms MGUS and smoldering myeloma. Up to 36 participants will receive two infusions of their own T cells that have been engineered to recognize …
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: PHASE1 • Sponsor: Baylor College of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Diet and supplements tested to stop blood cancer before it starts
Prevention Recruiting nowThis study tests whether a plant-based diet or supplements (omega-3 and curcumin) can change gut bacteria in people with MGUS or smoldering multiple myeloma, conditions that can lead to multiple myeloma. Researchers will measure butyrate levels in stool, a sign of healthy gut bac…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Prevention
Last updated Jun 27, 2026 12:08 UTC
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Fasting and mediterranean diet tested in blood cancer patients
Symptom relief Recruiting nowThis study looks at whether a diet that includes longer overnight fasting and follows a Mediterranean eating pattern is practical for people with multiple myeloma or its early forms (MGUS or smoldering myeloma). About 120 adults will try this approach to see if they can stick wit…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: NA • Sponsor: University of Miami • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Gene clues may unlock new treatments for bone marrow cancer
Knowledge-focused Recruiting nowThis study investigates whether changes in the GBA and PSAP genes are more common in people with multiple myeloma or its precursor condition, MGUS. Researchers will compare the frequency of these gene variants in 300 patients against known population databases. The goal is to bet…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:07 UTC
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Can we predict myeloma before it starts? new study aims to find out
Knowledge-focused Recruiting nowThe PROMISE study is enrolling 30,000 people at high risk for multiple myeloma, including African Americans and those with a family history of blood cancers. Participants provide blood samples so researchers can track changes over time and identify who progresses to myeloma. The …
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Dana-Farber Cancer Institute • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Hunting for clues: study seeks to predict myeloma before it starts
Knowledge-focused Recruiting nowThis observational study follows 200 people with early blood conditions (MGUS or smoldering myeloma) that sometimes turn into multiple myeloma. Researchers will track age, blood protein levels, bone marrow cells, genes, and bone health to find patterns that predict progression. N…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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New study asks: how do early blood disorders really affect daily life?
Knowledge-focused Recruiting nowThis study looks at the quality of life of people with two early blood conditions: MGUS and smoldering myeloma. Researchers will ask 400 participants to fill out short questionnaires about their symptoms and concerns. The goal is to learn what matters most to patients, not to tes…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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Firefighter blood study seeks to uncover cancer clues
Knowledge-focused Recruiting nowThis study looks at whether firefighters' exposure to hazardous chemicals leads to pre-cancerous changes in their blood. Researchers will collect blood samples from 300 firefighters aged 40-49 with at least 5 years on the job. The goal is to find early markers that might predict …
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Wake Forest University Health Sciences • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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New italian network aims to catch rare blood disease earlier
Knowledge-focused Recruiting nowThis study is creating a network of hospitals in Italy to find and treat AL amyloidosis earlier. Researchers will screen people with certain blood conditions (MGUS or smoldering myeloma) using special tests. The goal is to speed up diagnosis, connect patients to the right care, a…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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1,000 volunteers help scientists unlock the mystery of myeloma progression
Knowledge-focused Recruiting nowThis study is for 1,000 adults with early blood conditions called MGUS or smoldering multiple myeloma. Researchers want to find out why some people's conditions stay stable while others progress to active multiple myeloma. Participants will provide samples and have regular check-…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: University of Miami • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:06 UTC
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Ohio study aims to track and support rare blood cancer patients
Knowledge-focused Recruiting nowThis study is creating a database of up to 5,000 people in Ohio with plasma cell disorders like multiple myeloma and amyloidosis. Researchers will track treatments, outcomes, and quality of life, while also offering patients access to expert consultations and information about su…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Mayo clinic launches gut bacteria study for rare plasma cell disorders
Knowledge-focused Recruiting nowThis study looks at the gut microbiome (the bacteria living in the digestive system) of people with POEMS syndrome, multiple myeloma, MGUS, AL amyloidosis, and healthy household members. Participants provide stool samples at home using a collection kit. The goal is to understand …
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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Simple blood test may uncover rare diseases in myeloma patients
Knowledge-focused Recruiting nowThis study aims to find out how many people with an enlarged spleen or certain blood disorders (like multiple myeloma) also have Gaucher disease or acid sphingomyelinase deficiency (ASMD). Researchers will use a simple blood spot test to check for these rare conditions. The goal …
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Fundación Española de Hematología y Hemoterapía • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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New PET tracer could spot Hard-to-See cancers
Knowledge-focused Recruiting nowThis early-phase study is testing a new imaging agent called [68Ga]-pentixafor to see how well it shows up on PET/CT scans in people with certain blood cancers (like multiple myeloma and non-Hodgkin lymphoma) and rare immune cell tumors. About 30 participants will get the agent a…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: EARLY_PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:02 UTC
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Family history of blood cancer? new study aims to catch myeloma early
Knowledge-focused Recruiting nowThis study is looking for 2,000 people who have a close family member with a blood cancer like multiple myeloma. The goal is to find early warning signs of the disease by collecting blood samples and health information over time. Participants will not receive any treatment, but t…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Tel-Aviv Sourasky Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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Can a plant-based diet boost gut health in blood cancer precursors?
Knowledge-focused Recruiting nowThis study looks at how a short-term plant-based diet or supplements (omega-3, curcumin, or probiotics) change levels of butyrate—a healthy gut compound—in people with smoldering multiple myeloma or MGUS. About 200 participants will be randomly assigned to one of the diet or supp…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC
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Could sleep apnea affect bone marrow in blood cancer patients?
Knowledge-focused Recruiting nowThis study looks at sleep apnea in people with MGUS or multiple myeloma, two plasma cell disorders. Researchers will collect bone marrow samples during routine biopsies to compare gene activity in patients with and without sleep apnea. The goal is to understand if sleep apnea inf…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Michael Tomasson • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC