MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Clinical trials for MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE explained in plain language.
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Promising nerve pain drug trial for MGUS patients abruptly withdrawn
Disease control TerminatedThis study aimed to see if the drug daratumumab could improve nerve damage (peripheral neuropathy) in people with a blood condition called MGUS. Participants would have received weekly injections for two months, then every other week for four more months. However, the trial was w…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: PHASE2 • Sponsor: Georgetown University • Aim: Disease control
Last updated May 17, 2026 02:16 UTC
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Plant-Based diet trial aims to stop blood cancer before it starts
Prevention OngoingThis study tests whether a plant-based diet is practical for overweight people with early blood conditions called MGUS or smoldering multiple myeloma. Researchers will see if participants can stick to the diet and lose weight, and whether it helps prevent progression to multiple …
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: NA • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Prevention
Last updated May 17, 2026 02:03 UTC
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Diabetes drug metformin tested to halt blood cancer before it starts
Prevention OngoingThis study tests whether metformin, a common diabetes medicine, can stop early blood conditions (MGUS and smoldering multiple myeloma) from turning into multiple myeloma. About 60 participants will receive either metformin or a placebo pill. Researchers will track changes in bloo…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Prevention
Last updated May 11, 2026 20:49 UTC
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Could a simple blood test spot cancer risk years early?
Knowledge-focused ENROLLING_BY_INVITATIONThis study screens 1,000 adults aged 40 and older for MGUS, a condition with an abnormal blood protein that can sometimes lead to a blood cancer called multiple myeloma. Researchers at Mayo Clinic want to learn how genetics and the immune system affect MGUS across different ethni…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 17, 2026 02:02 UTC
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Iceland screens 80,000 for hidden cancer risk
Knowledge-focused OngoingThis study looks at whether screening healthy people for a condition called MGUS can help find multiple myeloma earlier and improve survival. Over 80,000 adults in Iceland were invited to participate. The goal is to see if early detection leads to better outcomes and fewer compli…
Matched conditions: MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE
Phase: NA • Sponsor: University of Iceland • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC