Diet and supplements tested to stop blood cancer before it starts

NCT ID NCT05640843

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a plant-based diet or supplements (omega-3 and curcumin) can change gut bacteria in people with MGUS or smoldering multiple myeloma, conditions that can lead to multiple myeloma. Researchers will measure butyrate levels in stool, a sign of healthy gut bacteria. The goal is to find a way to prevent progression to active cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Whole foods plant-based diet, algae omega-3 plus curcumin supplements

What this could lead to

If successful, this could point toward a dietary or supplement approach to slow or prevent progression of MGUS or smoldering multiple myeloma to active multiple myeloma.

What could go wrong

This is an early, small study (180 participants) looking at a biomarker (butyrate levels) rather than clinical outcomes like disease progression. The diet and supplements may not change gut bacteria enough to affect the disease, and results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

monoclonal gammopathy of uncertain significance Smoldering Multiple Myeloma smoldering plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Emory University (Data Collection Only)

    RECRUITING

    Atlanta, Georgia, 30322, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

    RECRUITING

    Basking Ridge, New Jersey, 07920, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Bergen (All Protocol Activities)

    RECRUITING

    Montvale, New Jersey, 07645, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Cancer Center (All Protocol Activities)

    RECRUITING

    New York, New York, 10065, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Monmouth (All Protocol Activities)

    RECRUITING

    Middletown, New Jersey, 07748, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Nassau (All Protocol Activities)

    RECRUITING

    Uniondale, New York, 11553, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Suffolk- Commack (All Protocol Activities)

    RECRUITING

    Commack, New York, 11725, United States

    Contact Phone: •••-•••-••••

  • Memorial Sloan Kettering Westchester (All Protocol Activities)

    RECRUITING

    Harrison, New York, 10604, United States

    Contact Phone: •••-•••-••••