MICROBIOME

This study is looking for better ways to detect colorectal cancer early by analyzing bacteria in stool samples. Researchers will collect samples from 30,000 people aged 40-74 in the Lisbon area and compare their gut microbiome with colonoscopy results. The goal is to find bacteri…

This study is looking for 400 adults in Portugal, aged 40 to 74, who have recently been diagnosed with colorectal cancer but have not yet started treatment. Researchers want to see if the types and genes of bacteria in a person's stool can help detect cancer earlier, especially i…

This study tests whether an online program teaching a high-fiber, gut-healthy diet is feasible for women with triple-negative breast cancer who are receiving immunotherapy and chemotherapy. The goal is to see if the diet can improve treatment response and reduce side effects. Six…

This study tests whether giving parents of C-section babies personalized gut health reports and advice can improve their infant's gut bacteria and reduce early signs of allergies like eczema. Researchers will compare three groups: one gets full guidance, another gets basic tips, …

This study looks at whether gently swabbing the nose of a baby born by C-section with a small amount of their mother's vaginal fluids is safe and can change the germs living in their nose. About 20 healthy babies will take part, and half will get the real swab while the other hal…

This study looks at how a special oil changes the bacteria in the guts of 25 healthy adults. Participants will take the oil for one month and provide stool and capsule samples. The goal is to learn more about gut health, not to treat any disease.

This study looks at the bacteria and their antibiotic resistance genes in 800 people with pneumonia. Researchers will compare severe and mild cases to understand which resistance genes are present. The goal is to improve how doctors diagnose and treat pneumonia by knowing which a…

This study explores whether bacteria in the mouth and gut can help detect pancreatic cancer earlier. Researchers will collect samples from 300 people with suspected pancreatic lesions. The goal is to find microbial patterns that improve diagnosis and treatment planning.

This study looks at how different oral hygiene routines (including mouthwash) affect the bacteria in your mouth, gum inflammation, and overall gum health in people with gingivitis. Over 6 weeks, 250 adults will use assigned products twice daily, with a follow-up 2 weeks after sto…

This study looks at how the bacteria and natural chemicals in couples' bodies might influence the success of IVF treatment. Researchers will collect samples from 1000 couples to see if these factors are linked to pregnancy, miscarriage, or live birth. The goal is to better unders…

This study looks at how severe injuries change the brain, bone marrow, and gut, and how these changes cause long-term anemia and slow recovery. Researchers will study 275 adults with serious blunt trauma to understand these interactions. The goal is to find new ways to help peopl…

This study follows 600 burn patients and 60 healthy people for up to 2 years to see how burns change the bacteria on the skin and in the gut. Researchers will collect samples and measure skin health at several time points. The goal is to better understand healing and find new way…

This study looks at how cannabis ingredients (CBD and THC) impact inflammation and brain health in people with HIV. Researchers will give 90 participants both compounds in different orders over 6 weeks, then measure blood markers and brain barriers. The goal is to understand how …

This study looks at why some breast cancer patients get diarrhea from the drug Abemaciclib while others don't. Researchers will compare the gut bacteria of 60 women who are already taking the drug. The goal is to find if certain bacteria protect against diarrhea, which could lead…

This study looks at how different sweeteners affect the mouth's acidity and dental plaque in teenagers. About 52 teens who regularly drink soda will try plain water, water with stevia (a no-calorie sweetener), and water with sugar. Researchers will measure changes in saliva and p…