Gut bacteria could hold key to better colon cancer detection
NCT ID NCT06741293
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to improve early detection of colorectal cancer by analyzing gut bacteria in stool samples from 30,000 people in Portugal aged 40-74. Researchers will compare the microbiome of healthy individuals with those who have precancerous polyps or cancer, looking for unique bacterial signatures. The goal is to develop a more accurate, non-invasive screening test than current methods like the FIT test.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this could lead to a more accurate, non-invasive stool test for early colorectal cancer detection, potentially saving lives through earlier diagnosis.
What could go wrong
This is an observational study, not a treatment trial. It may not identify reliable biomarkers, and any new test would require further validation in larger studies before clinical use.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Gulbenkian Institute for Molecular Medicine
RECRUITINGLisbon, Lisbon District, 1649-028, Portugal
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••