COLORECTAL CANCER SCREENING

This study compares a new technique called total underwater colonoscopy (using water instead of gas) to the standard method in over 1,000 people undergoing screening after a positive stool test. The goal is to see if water helps doctors find more flat, hard-to-spot polyps that ca…

This study is developing a blood test that looks for tiny genetic molecules called miRNAs, which can signal the presence of several gastrointestinal cancers like liver, pancreatic, and colorectal cancer. Researchers will analyze blood samples from 1,000 adults—half with cancer an…

This study tests whether giving personalized diet and lifestyle advice to people who had a positive colorectal cancer screening (but no cancer) can help them adopt healthier habits and potentially prevent future cancer. 800 participants will be randomly assigned to receive the ad…

This study tests whether mixing an electrolyte beverage with water improves the quality and tolerability of bowel preparation before colonoscopy. 405 adults scheduled for colonoscopy will be randomly assigned to drink polyethylene glycol (PEG) with water only, or with a low or me…

This study compares two FDA-approved bowel preparation methods for colonoscopy: low-volume tablets (Suflave/Sutab) versus the standard Golytely drink. About 300 adults scheduled for a colonoscopy will be randomly assigned to one of the two options. The goal is to see which method…

This study tests an online decision aid called Protect Your Colon™ that helps people aged 45-75 choose a colorectal cancer screening test. Participants will use the tool or get usual care, and researchers will see if the tool increases screening completion within 6 months. The go…

This study aims to improve early detection of colorectal cancer by analyzing gut bacteria in stool samples from 30,000 people in Portugal aged 40-74. Researchers will compare the microbiome of healthy individuals with those who have precancerous polyps or cancer, looking for uniq…

This study tests whether a culturally tailored education program helps more people complete colorectal cancer screening. About 50 adults aged 45-75 who are not up-to-date with screening will take part. The program aims to improve screening rates by addressing beliefs and barriers…

This study tests whether using a patient's existing CT scan to guide the colonoscope can make the procedure faster, less painful, and easier for doctors. About 200 adults getting a colonoscopy will be randomly assigned to standard or CT-assisted insertion. The goal is to see if t…

This study tests whether giving general practitioners face-to-face training in patient-centered care helps them make better shared decisions with patients about colorectal cancer screening. About 400 patients aged 50 to 74 who are eligible for screening will take part. The main g…

This study talks to patients aged 45-54 and health center staff to find out what makes it hard to get colorectal cancer screening. Researchers will interview participants and survey staff to learn about barriers and what might help. The goal is to improve screening rates in this …

This study looks at why some people don't get a follow-up colonoscopy after a positive FIT stool test and tests simple strategies to help them complete it. Researchers will work with 45 patients from Codman Square Health Center to find out what works best. The goal is to make sur…