Could water replace gas in colonoscopies for better polyp detection?

NCT ID NCT06333392

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new technique called total underwater colonoscopy (using water instead of gas) to the standard method in over 1,000 people undergoing screening after a positive stool test. The goal is to see if water helps doctors find more flat, hard-to-spot polyps that can lead to cancer, while also reducing pain and the need for repeat procedures. If successful, this simple change could make screening more effective and comfortable, especially for women.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm syncope, familial vasovagal Syncope, Vasovagal

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Akershus University Hospital Health Trust

    RECRUITING

    Lørenskog, 1478, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Sahlgrenska University Hospital, Gothenburg, Region Västra Götaland, Sweden, Department of Medicine, Geriatrics and Emergency Care Mölndal

    NOT_YET_RECRUITING

    Gothenburg, Sweden

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ullevål University Hospital Health Trust

    RECRUITING

    Oslo, 0424, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Vestre Viken Health Trust, Bærum Hospital

    RECRUITING

    Drammen, 3004, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Østfold Hospital Health Trust

    RECRUITING

    Grålum, 1714, Norway

    Contact Phone: •••-•••-•••• Email: •••••@•••••