Trauma's hidden toll: scientists map Brain-Bone-Gut damage
NCT ID NCT06606119
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how severe traumatic injury changes the bone marrow and gut, leading to long-term anemia and microbiome disruption. Researchers will collect bone marrow, blood, and stool samples from 275 adults with serious blunt trauma. The goal is to understand these interactions so future treatments can be developed to improve recovery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this research could identify new targets for treatments that improve recovery from severe trauma, especially for persistent anemia and gut health issues.
What could go wrong
This is an observational study, not testing a treatment. It is early-stage research, and findings may not lead directly to new therapies.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UF Academic Research Building
RECRUITINGGainesville, Florida, 32610, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UF Health at Shands Hospital
RECRUITINGGainesville, Florida, 32610, United States
Contact
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UF Laboratory of Inflammation Biology and Surgical Science and Shands Hospital at UF
RECRUITINGGainesville, Florida, 32610, United States
Contact