METASTATIC SOLID TUMOR
Clinical trials for METASTATIC SOLID TUMOR explained in plain language.
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New pill targets Cancer's DNA repair in advanced tumor trial
Disease control OngoingThis study is testing a new oral drug called ART6043 for people with advanced or metastatic solid tumors. It will check the safety and early signs of effectiveness of ART6043 when taken by itself and when combined with an existing cancer drug, olaparib. The trial will enroll abou…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Artios Pharma Ltd • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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First human test of new 'Living Drug' for Tough-to-Treat cancers
Disease control OngoingThis is a first-in-human study to check the safety of a new, personalized cell therapy called M-CENK, given with a drug named N-803, for adults with advanced solid tumors that have spread or stopped responding to other treatments. The therapy involves collecting a patient's own i…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: ImmunityBio, Inc. • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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New drug combo tested for Tough-to-Treat cancers
Disease control OngoingThis early-stage study is testing a new drug called DCC-3116, both by itself and combined with other cancer drugs, for people with advanced solid tumors that have specific genetic changes. The main goals are to find safe doses and see if the treatments can shrink tumors. It is fo…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Deciphera Pharmaceuticals, LLC • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope drug enters human testing for Tough-to-Treat cancers
Disease control OngoingThis is the first study in humans testing a new drug called DS-1055a. It aims to find a safe dose and check for side effects in 40 adults with advanced solid tumors that have returned or stopped responding to available treatments. The main goal is to understand how the body handl…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Daiichi Sankyo • Aim: Disease control
Last updated Mar 30, 2026 14:27 UTC
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New Long-Acting cancer drug seeks to boost immune system against tumors
Disease control OngoingThis early-stage trial is testing a new long-acting immunotherapy drug called TransCon IL-2 β/γ in adults with advanced solid tumors that have spread or cannot be removed by surgery. The study aims to find safe doses and see if the drug, given alone or with other cancer treatment…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Ascendis Pharma Oncology Division A/S • Aim: Disease control
Last updated Mar 23, 2026 15:17 UTC
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New 'Pan-KRAS' drug enters human testing for multiple Hard-to-Treat cancers
Disease control OngoingThis is an early-stage trial to test the safety and determine the right dose of a new experimental drug called LY4066434. The drug is designed to block a common cancer-driving protein called KRAS in people with advanced solid tumors, including pancreatic, lung, and colorectal can…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Mar 19, 2026 14:56 UTC
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New cancer drug enters first human trials for Tough-to-Treat tumors
Disease control OngoingThis is a first-in-human study to test the safety and early effectiveness of a new investigational drug called WTX-124. It will be given alone and in combination with an existing immunotherapy (pembrolizumab) to about 150 adults with advanced or metastatic solid tumors that have …
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Werewolf Therapeutics, Inc. • Aim: Disease control
Last updated Mar 17, 2026 13:09 UTC
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New 'Smart Bomb' drug tested for Tough-to-Treat advanced cancers
Disease control OngoingThis study tested an experimental drug called sacituzumab govitecan in people with advanced solid tumors that had spread and stopped responding to standard treatments. The drug is designed to deliver chemotherapy directly to cancer cells. Researchers measured how well the tumors …
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE2 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated Mar 16, 2026 15:23 UTC
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Research probes survival gap for native americans on cancer immunotherapy
Knowledge-focused OngoingThis study looks back at medical records to understand how well immunotherapy cancer drugs work for American Indian patients compared to White patients. Researchers will analyze survival times, side effects, and cancer-related deaths in 72 patients who were treated between 2015 a…
Matched conditions: METASTATIC SOLID TUMOR
Sponsor: University of Oklahoma • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:01 UTC