Experimental virus injected into tumors shows early promise, but trial on hold

NCT ID NCT05938296

Terminated Disease control Sponsor: Binhui Biopharmaceutical Co., Ltd. Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a modified herpes virus (BS006) that is injected directly into tumors to kill cancer cells and activate the immune system. It involves 29 adults with advanced solid tumors like melanoma or breast cancer. The study is currently suspended, and its main goals are to check safety and find the right dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: BS006 (a modified herpes virus designed to infect and kill cancer cells and boost immune response)
What this could lead to: If it works, this could point toward a new treatment option for advanced solid tumors that are hard to treat with standard therapies.
What could go wrong: This is a very early Phase 1 trial with only 29 participants, currently suspended. The main goal is safety, not effectiveness, and many early-stage cancer treatments fail to show benefit.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

breast carcinoma melanoma metastatic malignant neoplasm metastatic melanoma neoplasm skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SOLID TUMOR

Contacts and locations

Locations

Barbara Ann Karmanos Cancer Hospital dba Karmanos Cancer Center

Detroit, Michigan, 48201, United States
Orlando Health Cancer Institute

Orlando, Florida, 32806, United States

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