Experimental virus injected into tumors shows early promise, but trial on hold

NCT ID NCT05938296

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tests a modified herpes virus (BS006) that is injected directly into tumors to kill cancer cells and activate the immune system. It involves 29 adults with advanced solid tumors like melanoma or breast cancer. The study is currently suspended, and its main goals are to check safety and find the right dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

BS006 (a modified herpes virus designed to infect and kill cancer cells and boost immune response)

What this could lead to

If it works, this could point toward a new treatment option for advanced solid tumors that are hard to treat with standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 29 participants, currently suspended. The main goal is safety, not effectiveness, and many early-stage cancer treatments fail to show benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

breast carcinoma melanoma metastatic malignant neoplasm metastatic melanoma neoplasm skin squamous cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Barbara Ann Karmanos Cancer Hospital dba Karmanos Cancer Center

    Detroit, Michigan, 48201, United States

  • Orlando Health Cancer Institute

    Orlando, Florida, 32806, United States