METASTATIC SOLID TUMOR
Clinical trials for METASTATIC SOLID TUMOR explained in plain language.
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New pill shows promise in shrinking Hard-to-Treat breast tumors
Disease control CompletedThis study tested a new oral drug called BGB-43395 in 33 Chinese patients with advanced or metastatic HR+/HER2- breast cancer and other solid tumors. The drug blocks a protein (CDK4) that helps cancer cells grow. The goal was to find a safe dose and see if it can shrink tumors wh…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated Jun 27, 2026 13:06 UTC
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Diabetes drug plus chemo shows promise in early cancer trial
Disease control CompletedThis early-phase trial tested the safety of combining pioglitazone (a diabetes drug) with carboplatin (a chemotherapy) in 14 people with advanced solid tumors that could not be cured with standard treatments. The goal was to find the best dose and see if the combination is safe. …
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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New drug targets Hard-to-Treat cancers with rare gene mutation
Disease control CompletedThis early-stage study tested a new drug called PRT3789, alone or with chemotherapy (docetaxel), in people with advanced solid tumors that have a specific change in the SMARCA4 gene. The main goals were to check safety, find the best dose, and see if the drug shrinks tumors. 135 …
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Prelude Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New combo therapy shows promise for Hard-to-Treat cancers
Disease control CompletedThis early-stage trial tested a new drug called vibostolimab, either alone or combined with other cancer drugs, in 474 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check safety, find the right dose, and see if the dr…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New cocktail of immune drugs shows promise for tough prostate cancer
Disease control CompletedThis study tested different combinations of immunotherapy drugs in 59 adults with advanced prostate cancer that no longer responds to hormone therapy. The goal was to see if these combinations are safe and can help shrink tumors or lower PSA levels. Participants received up to fo…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Experimental immune therapy takes on stage IV cancers
Disease control CompletedThis early-stage trial tested a combination of immune cells in 9 people with stage IV solid tumors that had stopped responding to standard treatments. The main goal was to see if the therapy is safe and to check for any signs that it might control the disease. The study is now co…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Seoul Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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First human trial of SUPLEXA cells targets Hard-to-Treat cancers
Disease control CompletedThis early-stage trial tested a new therapy called SUPLEXA in 46 adults with advanced solid tumors or blood cancers that had spread. SUPLEXA is made from a patient's own immune cells, which are processed in a lab to become more active against cancer. The main goal was to check sa…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Alloplex Biotherapeutics Inc • Aim: Disease control
Last updated Jun 26, 2026 18:11 UTC
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New cancer drug EVT801 tested in humans for first time
Disease control CompletedThis early-stage trial tested an experimental drug called EVT801 in 32 adults with advanced solid tumours that had stopped responding to standard treatments. The main goal was to check the drug's safety and find the best dose to use in future studies. Participants took EVT801 cap…
Matched conditions: METASTATIC SOLID TUMOR
Phase: PHASE1 • Sponsor: Kazia Therapeutics Limited • Aim: Disease control
Last updated Jun 26, 2026 13:12 UTC