METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Clinical trials for METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA explained in plain language.
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Two-Pronged attack on advanced head and neck cancer enters major trial
Disease control Recruiting nowThis study is testing a new drug called ficerafusp alfa, which is designed to attack cancer cells in two ways at once. It is being given alongside an existing immunotherapy drug (pembrolizumab) to people with advanced head and neck cancer that has returned or spread. The goal is …
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Bicara Therapeutics • Aim: Disease control
Last updated Apr 01, 2026 18:41 UTC
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New Two-Drug attack on Tough-to-Treat cancers begins human testing
Disease control Recruiting nowThis early-stage trial is testing the safety and initial effectiveness of a new oral drug, STC-15, when given alongside an existing immunotherapy called toripalimab. It will enroll about 188 adults with specific advanced cancers—including lung, melanoma, endometrial, and head/nec…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: STORM Therapeutics LTD • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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New immune cell therapy combo aims to fight tough head & neck cancers
Disease control Recruiting nowThis study is testing whether a combination of three treatments—a modified immune cell infusion, an immune-stimulating protein, and an approved targeted antibody—is safe and effective for people with advanced head and neck cancer that has returned or spread. It is for patients wh…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Glenn J. Hanna • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New drug duo aims to outsmart tough cancers that resist standard treatment
Disease control Recruiting nowThis study is testing whether combining two drugs, cabozantinib and nivolumab, can help control advanced melanoma or head and neck cancer that has worsened despite standard immunotherapy. It will enroll about 150 adults whose cancer has progressed on prior treatment. A key goal i…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:32 UTC
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Cholesterol drug may boost cancer treatment in new trial
Disease control Recruiting nowThis study is testing whether adding the common cholesterol-lowering drug lovastatin to the immunotherapy drug pembrolizumab can better control head and neck cancer that has returned or spread. Researchers believe lovastatin may make cancer cells more vulnerable to the immune sys…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Tiny radiation seeds target tough head and neck cancers
Disease control Recruiting nowThis study is testing a new combination treatment for people with advanced head and neck cancer that has come back or spread. Doctors will place tiny, temporary radioactive seeds directly into the tumor to deliver a high dose of radiation, while patients also receive a standard i…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Alpha Tau Medical LTD. • Aim: Disease control
Last updated Mar 25, 2026 14:08 UTC
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Blood pressure pill joins fight against tough head & neck cancers
Disease control Recruiting nowThis early-stage study is testing if a three-part treatment is safe and effective for people with head and neck cancer that has come back, spread a little, or hasn't responded to other treatments. The treatment combines a common blood pressure drug (losartan), an immunotherapy dr…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Disease control
Last updated Mar 23, 2026 15:19 UTC
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Custom-Made vaccine aims to train immune system to fight advanced cancers
Disease control Recruiting nowThis study is testing a new, personalized vaccine designed to target the unique proteins on a patient's own cancer cells. It is being given alongside an existing immunotherapy drug (pembrolizumab) to see if the combination is safe and can help control advanced solid tumors that h…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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Doctors test custom vaccine to fight returning head and neck cancer
Disease control Recruiting nowThis early-stage study is testing a personalized vaccine made from a patient's own tumor cells. It aims to see if the vaccine, given alone or with an immunotherapy drug (pembrolizumab), is safe and can help the immune system fight advanced head and neck cancer that has returned o…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Emory University • Aim: Disease control
Last updated Mar 20, 2026 14:48 UTC
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New hope for Tough-to-Treat head and neck cancers: can a drug duo outperform the standard?
Disease control Recruiting nowThis study is for people with advanced head and neck cancer that has returned or spread and has stopped responding to standard platinum-based chemotherapy. It aims to see if combining two immunotherapy drugs (pembrolizumab and cetuximab) helps patients live longer than using pemb…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Cancer care comes home: mayo clinic tests At-Home immunotherapy shots
Disease control Recruiting nowThis study is testing whether giving a cancer immunotherapy treatment called nivolumab as an injection at home is a safe and practical alternative to receiving it at a clinic. It aims to see if home treatment reduces the burden of travel and improves quality of life for patients …
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 16, 2026 15:27 UTC
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New hope for patients when standard immunotherapy stops working
Disease control Recruiting nowThis study is testing if a drug called cetuximab can help control head and neck cancer that has returned or spread after standard immunotherapy has stopped working. It will involve about 38 adults who have already tried a PD-1 inhibitor drug. The main goal is to see if the cancer…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Mar 09, 2026 14:25 UTC
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New scan aims to spot hidden cancer spread
Diagnosis Recruiting nowThis study is testing a new imaging agent to see if it can better detect when head and neck cancer has spread to other parts of the body. Researchers will give 60 participants an infusion of the experimental agent and then perform a special PET/CT scan. They will compare the resu…
Matched conditions: METASTATIC HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE1 • Sponsor: Eben Rosenthal • Aim: Diagnosis
Last updated Mar 27, 2026 12:38 UTC