MELASMA
Clinical trials for MELASMA explained in plain language.
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Stem cell exosomes and laser team up to fight stubborn melasma
Disease control CompletedThis study tested whether a combination of umbilical cord stem cell exosomes and a special laser can treat melasma, a stubborn skin condition causing dark patches on the face. Thirty adults with melasma received the treatment. The goal was to reduce the size and darkness of the p…
Matched conditions: MELASMA
Phase: NA • Sponsor: Fujian Medical University Union Hospital • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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Needle vs. pill: which melasma treatment wins?
Symptom relief CompletedThis study tested whether injecting tranexamic acid into the skin works better than taking it as a pill for melasma, a common skin condition causing dark patches. 218 adults with melasma took part. Researchers measured how much the dark patches improved after 8 weeks using a stan…
Matched conditions: MELASMA
Phase: EARLY_PHASE1 • Sponsor: Hayat Abad Medical Complex, Peshawar • Aim: Symptom relief
Last updated May 15, 2026 11:57 UTC
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New gel vs standard cream: which fades melasma better?
Symptom relief CompletedThis study tested two creams for melasma, a skin condition causing dark patches on the face. 34 adults used either a triple combination cream or a metformin gel every night for 12 weeks, plus sunscreen during the day. Researchers measured how much the dark spots improved to see w…
Matched conditions: MELASMA
Phase: NA • Sponsor: Jinnah Postgraduate Medical Centre • Aim: Symptom relief
Last updated May 11, 2026 20:51 UTC
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Cream showdown: which fades dark spots better?
Symptom relief CompletedThis study tested two creams—20% azelaic acid and 4% hydroquinone—on 146 adults with melasma, a condition causing dark patches on the face. Participants applied the cream daily for 12 weeks, and doctors checked how much the patches faded each month. The goal was to see which crea…
Matched conditions: MELASMA
Phase: NA • Sponsor: Gujranwala medical college District Headquarters Hospital, Gujranwala • Aim: Symptom relief
Last updated May 06, 2026 16:03 UTC
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New needle treatment may fade melasma in darker skin
Symptom relief CompletedThis study tested whether radiofrequency microneedling (RFMN) can safely treat melasma, a condition causing dark patches on the face, in people with darker skin (Fitzpatrick types IV-VI). Ten adults completed the treatment, and researchers measured changes in melasma severity usi…
Matched conditions: MELASMA
Phase: NA • Sponsor: The Cleveland Clinic • Aim: Symptom relief
Last updated Apr 30, 2026 15:49 UTC
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Screen light and melasma: new study finds no major risk
Knowledge-focused CompletedThis study looked at whether blue light from computer or TV screens can darken melasma, a common skin condition causing dark patches on the face. Twelve women with melasma had one side of their face exposed to simulated screen blue light for 5 days, while the other side was not e…
Matched conditions: MELASMA
Phase: NA • Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Knowledge-focused
Last updated May 17, 2026 09:21 UTC