Can new serums outshine hydroquinone for melasma?
NCT ID NCT07644871
First seen Jun 16, 2026
Summary
This 4-week pilot study tested two brightening serums against 4% hydroquinone in 18 adults with hyperpigmentation or melasma. Each participant used different products on each side of their face to compare results. The goal was to see if the serums could improve skin tone evenness with fewer side effects.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Revision Skincare
Irving, Texas, 75063, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
brightening serums (cosmetics) and 4% hydroquinone
What this could lead to
If successful, these serums could offer a gentler alternative to hydroquinone for evening skin tone.
What could go wrong
This is a very small, short pilot study with only 18 participants, so results may not apply widely. Cosmetics are less potent than prescription treatments.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.