Cream showdown: which works better for dark spots?
NCT ID NCT07327983
First seen Jan 09, 2026
Summary
This study tested two creams—20% azelaic acid and 4% hydroquinone—on 146 adults with melasma, a condition causing dark patches on the face. Participants applied the cream daily for 12 weeks, and doctors tracked changes in patch size and color. The goal was to see which cream works better and if azelaic acid is a safe alternative to hydroquinone.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Gujranwala Medical College Hospital
Lahore, Punjab Province, +92, Pakistan
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.