Cream showdown: which fades dark spots better?

NCT ID NCT07327983

First seen Jan 09, 2026 · Last updated May 06, 2026 · Updated 20 times

Summary

This study tested two creams—20% azelaic acid and 4% hydroquinone—on 146 adults with melasma, a condition causing dark patches on the face. Participants applied the cream daily for 12 weeks, and doctors checked how much the patches faded each month. The goal was to see which cream works better and if azelaic acid is a safe alternative to hydroquinone.

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Contacts and locations

Locations

  • Gujranwala Medical College Hospital

    Lahore, Punjab Province, +92, Pakistan

Conditions

Explore the condition pages connected to this study.