Melasma treatment showdown: needle or pill?
NCT ID NCT07280234
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study in Pakistan compared two ways of giving tranexamic acid for melasma: tiny skin injections versus pills. 218 adults with melasma took part. Researchers measured changes in the Melasma Area and Severity Index after 8 weeks to see which method worked better.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid
What this could lead to
If it works, this could point toward a more effective or convenient way to treat melasma, a common skin condition causing dark patches.
What could go wrong
This is a small, early-phase study (218 people) with no blinding or long-term follow-up. Results may not apply to all skin types or guarantee lasting improvement.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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MTI-HMC Peshawar, Peshawar Khyber Pakhtunkhwa
Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan