Melasma treatment showdown: needle or pill?

NCT ID NCT07280234

Completed Disease control Sponsor: Hayat Abad Medical Complex, Peshawar Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study in Pakistan compared two ways of giving tranexamic acid for melasma: tiny skin injections versus pills. 218 adults with melasma took part. Researchers measured changes in the Melasma Area and Severity Index after 8 weeks to see which method worked better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: tranexamic acid
What this could lead to: If it works, this could point toward a more effective or convenient way to treat melasma, a common skin condition causing dark patches.
What could go wrong: This is a small, early-phase study (218 people) with no blinding or long-term follow-up. Results may not apply to all skin types or guarantee lasting improvement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MELASMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Melanosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MELASMA

Contacts and locations

Locations

MTI-HMC Peshawar, Peshawar Khyber Pakhtunkhwa

Peshawar, Khyber Pakhtunkhwa, 25000, Pakistan

More trials for these conditions

Other studies related to the condition(s) this trial covers.