MELANOMA

This is an early safety study to find a safe dose of an experimental virus therapy called DNX-2401 for advanced melanoma. The study will enroll about 50 adults whose melanoma has spread to the brain or other parts of the body. Doctors will inject the modified virus directly into …

This study aims to see if eating a high-fiber diet helps melanoma patients respond better to their immunotherapy treatment. Researchers will observe 60 patients already receiving standard immunotherapy drugs and track their diet, health, and treatment outcomes. The goal is to lea…

This is the first-ever study in humans of a new drug called DXC014, designed for people with advanced solid tumors like lung cancer, melanoma, and prostate cancer. The main goal is to find a safe dose and understand how the body processes the drug. Researchers will also look for …

This study aims to see if a new, potentially more affordable version of the cancer drug Opdivo (called Bmab1700) behaves similarly in the body. It will involve 120 adults whose melanoma has been completely removed by surgery. Participants will receive either the new drug or Opdiv…

This study is testing an experimental drug called N17350 for adults with advanced solid tumors that have spread or stopped responding to standard treatments. The drug is injected directly into a tumor every two weeks to try to stimulate the immune system to fight the cancer. The …

This is a first-in-human study testing a new oral drug called ACC-1898 in adults with advanced solid tumors who have run out of standard treatment options. The main goals are to find a safe dose and understand how the body processes the drug. Researchers will also look for early …

This is the first study in people testing a new drug called BI 3810944 for adults with advanced solid tumors or melanoma that have not responded to standard treatments. The main goals are to find a safe dose and see if the drug helps shrink tumors. Participants will receive the d…

This study is testing a phone app called FOCUS that teaches coping skills to help people with advanced cancer manage common symptoms like fatigue, anxiety, depression, and sleep problems. It aims to make this support more accessible to patients living in rural areas who may have …

This is a survey to find people who might qualify for one of several ongoing cancer genetics research studies. The goal is to better understand why some people and families get certain cancers. Participants fill out a 15-20 minute online questionnaire about their personal and fam…

This study aims to understand why cancer immunotherapy drugs sometimes cause serious side effects. Researchers suspect these drugs might change how the liver processes other medications patients are taking. The study will give 80 cancer patients a special cocktail of safe test dr…

This early-stage study aims to see if inhaling the cancer drug afatinib works similarly to taking it as a pill. It will involve 24 healthy adult smokers who will try both the inhaled and oral versions. Researchers will measure how much of the drug gets into the body and lungs to …