MALIGNANT PLEURAL MESOTHELIOMA
Clinical trials for MALIGNANT PLEURAL MESOTHELIOMA explained in plain language.
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Light therapy shows promise in tough mesothelioma fight
Disease control CompletedThis study tested a new approach for malignant pleural mesothelioma, a rare and aggressive lung cancer. Six patients received a combination of surgery, light-activated drug therapy (PDT), chemotherapy, and radiation. The goal was to see if this intense treatment plan was safe and…
Matched conditions: MALIGNANT PLEURAL MESOTHELIOMA
Phase: PHASE2 • Sponsor: University Hospital, Lille • Aim: Disease control
Last updated May 17, 2026 02:46 UTC
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Gene therapy cocktail shows promise for tough-to-treat mesothelioma
Disease control CompletedThis study tested a new approach for people with malignant pleural mesothelioma, a rare and aggressive lung cancer, who had already tried at least one treatment. It combined a gene therapy (rAd-IFN) given directly into the chest with two oral drugs (celecoxib and gemcitabine). Th…
Matched conditions: MALIGNANT PLEURAL MESOTHELIOMA
Phase: PHASE3 • Sponsor: Ferring Ventures Limited • Aim: Disease control
Last updated May 17, 2026 02:41 UTC
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Immunotherapy boosts chemo in tough lung cancer trial
Disease control CompletedThis study tested adding the immunotherapy drug durvalumab to standard chemotherapy for people with advanced pleural mesothelioma that cannot be removed by surgery. The goal was to see if the combination helps patients live longer. About 214 adults took part, receiving either the…
Matched conditions: MALIGNANT PLEURAL MESOTHELIOMA
Phase: PHASE3 • Sponsor: PrECOG, LLC. • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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New chemo delivery method shows promise for rare lung cancer
Disease control CompletedThis study tested a way to deliver strong chemotherapy drugs directly to the tumor in people with a rare lung cancer called malignant pleural mesothelioma that cannot be removed by surgery. The treatment, called transarterial chemoperfusion, uses a catheter to send cisplatin, met…
Matched conditions: MALIGNANT PLEURAL MESOTHELIOMA
Phase: PHASE2 • Sponsor: H. Lee Moffitt Cancer Center and Research Institute • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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Gene-Edited immune cells take on Hard-to-Treat cancers
Disease control CompletedThis early-phase trial tested a new treatment called CTX131 for adults with several types of advanced solid tumors that had stopped responding to standard therapies. CTX131 uses a patient's own immune cells that are edited with CRISPR technology to target a protein called CD70 on…
Matched conditions: MALIGNANT PLEURAL MESOTHELIOMA
Phase: PHASE1, PHASE2 • Sponsor: CRISPR Therapeutics AG • Aim: Disease control
Last updated May 13, 2026 15:58 UTC
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Could Pre-Surgery radiation stop mesothelioma from spreading?
Disease control CompletedThis study tested whether giving a short, intense course of radiation to the chest just before surgery can kill cancer cells and prevent them from spreading outside the chest during the operation. It involved 104 people with malignant pleural mesothelioma, a rare cancer linked to…
Matched conditions: MALIGNANT PLEURAL MESOTHELIOMA
Phase: PHASE1, PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 04, 2026 16:31 UTC
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French study checks Real-World results of new mesothelioma drug combo
Knowledge-focused CompletedThis study looked back at the medical records of 204 French patients with untreated, inoperable malignant pleural mesothelioma who received a combination of nivolumab and ipilimumab through an early access program. The goal was to see how well the treatment worked in everyday pra…
Matched conditions: MALIGNANT PLEURAL MESOTHELIOMA
Sponsor: Groupe Francais De Pneumo-Cancerologie • Aim: Knowledge-focused
Last updated May 15, 2026 11:57 UTC