Immunotherapy duo shows promise against rare lung cancer in chinese trial

NCT ID NCT05136677

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether a combination of two immunotherapy drugs (nivolumab and ipilimumab) works better than standard chemotherapy for Chinese patients with advanced pleural mesothelioma, a rare cancer of the lung lining. 102 patients who could not have surgery were randomly assigned to receive either the immunotherapy combo or chemotherapy. The main goal was to see if the immunotherapy helped patients live longer. The study is now complete.

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Conditions

The condition(s) this trial relates to.

malignant mesothelioma malignant pleural mesothelioma Mesothelioma, Malignant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Local Institution - 0001

    Shanghai, Shanghai Municipality, 200030, China

  • Local Institution - 0003

    Changchun, Jilin, 130021, China

  • Local Institution - 0004

    Shenyang, Liaoning, 110042, China

  • Local Institution - 0005

    Changsha, Hunan, 410013, China

  • Local Institution - 0006

    Zhengzhou, Henan, 450003, China

  • Local Institution - 0007

    Tianjin, Tianjin Municipality, 300052, China

  • Local Institution - 0009

    Beijing, Beijing Municipality, 100142, China

  • Local Institution - 0010

    Kunming, Yunnan, 650106, China

  • Local Institution - 0012

    Ningbo, Zhejiang, 315010, China

  • Local Institution - 0013

    Harbin, Heilongjiang, 150081, China

  • Local Institution - 0014

    Hangzhou, Zhejiang, 310003, China

  • Local Institution - 0015

    Yangzhou, Jiangsu, 225001, China

  • Local Institution - 0016

    Ningbo, Zhejiang, 315041, China

  • Local Institution - 0018

    Tianjin, Tianjin Municipality, 300060, China

  • Local Institution - 0020

    Hangzhou, Zhejiang, 310005, China

  • Local Institution - 0021

    Shenyang, Liaoning, 110044, China

  • Local Institution - 0023

    Wuhan, Hunan, 430023, China

  • Local Institution - 0029

    Chengdu, Sichuan, 610041, China

  • Local Institution - 0030

    Qingdao, Shandong, 266003, China

  • Local Institution - 0033

    Taiyuan, Shanxi, 030000, China

  • Local Institution - 0037

    Jinan, Shandong, 250117, China