Immunotherapy duo shows promise against rare lung cancer in chinese trial
NCT ID NCT05136677
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a combination of two immunotherapy drugs (nivolumab and ipilimumab) works better than standard chemotherapy for Chinese patients with advanced pleural mesothelioma, a rare cancer of the lung lining. 102 patients who could not have surgery were randomly assigned to receive either the immunotherapy combo or chemotherapy. The main goal was to see if the immunotherapy helped patients live longer. The study is now complete.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Local Institution - 0001
Shanghai, Shanghai Municipality, 200030, China
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Local Institution - 0003
Changchun, Jilin, 130021, China
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Local Institution - 0004
Shenyang, Liaoning, 110042, China
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Local Institution - 0005
Changsha, Hunan, 410013, China
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Local Institution - 0006
Zhengzhou, Henan, 450003, China
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Local Institution - 0007
Tianjin, Tianjin Municipality, 300052, China
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Local Institution - 0009
Beijing, Beijing Municipality, 100142, China
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Local Institution - 0010
Kunming, Yunnan, 650106, China
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Local Institution - 0012
Ningbo, Zhejiang, 315010, China
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Local Institution - 0013
Harbin, Heilongjiang, 150081, China
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Local Institution - 0014
Hangzhou, Zhejiang, 310003, China
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Local Institution - 0015
Yangzhou, Jiangsu, 225001, China
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Local Institution - 0016
Ningbo, Zhejiang, 315041, China
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Local Institution - 0018
Tianjin, Tianjin Municipality, 300060, China
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Local Institution - 0020
Hangzhou, Zhejiang, 310005, China
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Local Institution - 0021
Shenyang, Liaoning, 110044, China
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Local Institution - 0023
Wuhan, Hunan, 430023, China
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Local Institution - 0029
Chengdu, Sichuan, 610041, China
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Local Institution - 0030
Qingdao, Shandong, 266003, China
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Local Institution - 0033
Taiyuan, Shanxi, 030000, China
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Local Institution - 0037
Jinan, Shandong, 250117, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Chest-Injected drug drain Cancer's fluid trap?
- Can a pill that blocks multiple cancer proteins shrink Hard-to-Treat tumors?
- Abdominal chemotherapy after surgery may improve mesothelioma outcomes
- Engineered immune cells take aim at Mesothelin-Positive tumors
- New pill aims to shrink Hard-to-Treat cancers
- Triple-Drug cocktail targets Hard-to-Treat mesothelioma