French study checks if new combo works for mesothelioma in everyday practice

NCT ID NCT05308966

Completed Knowledge-focused Sponsor: Groupe Francais De Pneumo-Cancerologie Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks back at 204 patients with untreated, inoperable malignant pleural mesothelioma who received a combination of two immunotherapy drugs, nivolumab and ipilimumab, through an early access program in France. Researchers will collect data from medical records to see how long patients lived without the cancer getting worse and track side effects. The goal is to confirm the benefits seen in an earlier clinical trial and support making this treatment more widely available.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

nivolumab and ipilimumab

What this could lead to

If successful, this study could confirm that the nivolumab-ipilimumab combination works well in real-world patients, supporting its wider use and reimbursement for mesothelioma.

What could go wrong

This is a retrospective observational study, not a controlled trial, so results may be less reliable. It only looks at patients already treated, and outcomes may vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer malignant pleural mesothelioma mesothelioma Mesothelioma, Malignant

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALIGNANT PLEURAL MESOTHELIOMA UNRESECTABLE MALIGNANT NEOPLASM

Contacts and locations

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Locations

CAC Mougins

Mougins, 06250, France
CH Albi

Albi, 81013, France
CH Annecy Genevois

Pringy, 74374, France
CH Argenteuil

Argenteuil, 95010, France
CH Avignon

Avignon, 84000, France
CH Bastia

Bastia, 20200, France
CH Bayonne

Bayonne, 64100, France
CH Bligny

Bligny, 91640, France
CH Cannes

Cannes, 06400, France
CH Cornouaille

Quimper, 02900, France
CH Dijon Bourgogne

Dijon, 21000, France
CH Eure-Seine

Évreux, 27015, France
CH Libourne

Libourne, 33500, France
CH Nevers

Nevers, 58000, France
CH St Quentin

Saint-Quentin, 02321, France
CH Villefranche

Villefranche-sur-Saône, 69400, France
CH Villeurbanne

Villeurbanne, 69100, France
CH de Longjumeau

Longjumeau, 91160, France
CH de Saint Malo

St-Malo, 35400, France
CH du Cotentin

Cherbourg, 50102, France
CH du Mans

Le Mans, 72000, France
CHD les Oudaries

La Roche-sur-Yon, 85000, France
CHITS Toulon Sainte Musse

Toulon, 83056, France
CHRU Bretonneau

Tours, 37044, France
CHU Angers

Angers, 49033, France
CHU Besançon

Besançon, 25000, France
CHU Caen

Caen, 14033, France
CHU Hôpital Montpied

Clermont-Ferrand, 63000, France
CHU La Mileterie

Poitiers, 86021, France
CHU Lille

Lille, 59000, France
CHU Morvan

Brest, 29200, France
CHU Ponchailloux

Rennes, 35000, France
CHU du Pays d'Aix

Aix-en-Provence, 13616, France
Centre Antoine Lacassagne

Nice, 06149, France
Centre Léon Bérard

Lyon, 69373, France
Clinique Ambroise Paré

Beuvry, 63660, France
Clinique Bordeaux

Bordeaux, 33000, France
Clinique Gentilly

Gentilly, 94250, France
Clinique Pasteur

Brest, 29200, France
Clinique Saint Georges

Nice, 06000, France
Clinique Saint Grégoire

Rennes, 35000, France
Clinique de l'Estuaire

Saint-Nazaire, 44600, France
GH Le Havre

Le Havre, 76083, France
GH Paris Site St Joseph

Paris, 75674, France
HIA Begin

Saint-Mandé, 94160, France
HIA St Anne

Toulon, 83800, France
Hôpital Ambroise Paré

Boulogne-Billancourt, 92100, France
Hôpital Bichat

Paris, 75018, France
Hôpital Charles Nicolle

Rouen, 76031, France
Hôpital Cochin

Paris, 75014, France
Hôpital Haut-Lévèque - Groupe Hospitalier SUD

Pessac, 33604, France
Hôpital La Pitié-Salpêtrière

Paris, 75651, France
Hôpital Larrey

Toulouse, 31059, France
Hôpital Louis Pasteur

Colmar, 68000, France
Hôpital Louis Pradel

Bron, 69500, France
Hôpital Nord

Marseille, 13915, France
Hôpital du Scorff

Lorient, 56100, France
Hôpital privé de la Loire

Saint-Etienne, 42100, France
IPC

Marseille, 13009, France
Insititut de Cancerologie de l'Ouest

Saint-Herblain, 44805, France
Institut Curie

Paris, 75005, France
Les Hôpitaux Universitaires de Strasbourg

Strasbourg, 76091, France
Unicancer

Clermont-Ferrand, 63000, France