MALIGNANT PLEURAL MESOTHELIOMA

This early-stage trial tests an experimental drug called SAR445877, alone or with other cancer drugs, in adults with advanced solid tumors that have spread or cannot be removed. The study has two parts: first, finding a safe dose, and second, checking if the drug shrinks tumors. …

This early-phase trial is testing whether adding an immunotherapy drug (atezolizumab) and a personalized vaccine (WT1/DC) to standard chemotherapy can safely improve outcomes for people with a rare type of mesothelioma. The study plans to enroll 15 adults with epithelioid maligna…

This study tests whether proton beam therapy can help people with a rare cancer called malignant pleural mesothelioma. It involves 148 adults whose cancer is on one side of the chest. The goal is to see if this treatment can slow the cancer and help people live longer with fewer …

This study tests whether giving immunotherapy drugs (durvalumab and tremelimumab) alone or with chemotherapy before surgery can help prevent pleural mesothelioma from coming back. About 52 people with potentially removable tumors will take part. The main goal is to see if more th…

This study tests a new two-step treatment for people with malignant pleural mesothelioma, a rare and serious cancer of the lung lining. First, doctors use a special light therapy during a scope procedure to kill cancer cells. Then, patients receive an immunotherapy drug called ni…

This study is testing a new breath test, called an electronic nose (E-Nose), to see if it can measure how well treatment is working for people with malignant pleural mesothelioma (MPM). Researchers will collect breath samples from 20 patients before and during standard treatment,…

This research study is collecting tissue samples from 240 adults with malignant pleural mesothelioma to test a new method that combines molecular, radiological, and blood tests. The goal is to create a score that helps doctors predict how the disease will progress. Participants m…