New drug combo aims to stall rare lung cancer

NCT ID NCT07234058

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding an experimental immunotherapy (fianlimab) to standard treatment (cemiplimab plus chemotherapy) can better control pleural mesothelioma, a rare and aggressive cancer of the lung lining. About 126 people who have not yet been treated will receive one of two drug combinations. The goal is to see if the disease stays stable or shrinks for at least 6 months. This is not a cure; treatment continues as long as it works or up to 2 years.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pleural mesothelioma Mesothelioma, Malignant pleural mesothelioma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Aix-Pertuis - CHI

    Aix-en-Provence, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Amiens - CHU

    Amiens, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Angers - CHU

    Angers, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Avignon - CH

    Avignon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Besançon - CHU

    Besançon, 75009, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bordeaux - CHU

    Pessac, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Bordeaux - Institut Bergonié

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Boulogne - APHP Ambroise Paré

    Boulogne-Billancourt, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Caen - CHU

    Caen, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clermont-Ferrand - CHU

    Clermont-Ferrand, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Clermont-Ferrand - Centre Jean Perrin

    Clermont-Ferrand, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Créteil - CHI

    Créteil, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Dijon - Centre Georges-François Leclerc

    Dijon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Grenoble - CHU

    Grenoble, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • La Roche-Sur-Yon - CHD Vendée

    La Roche-sur-Yon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Le Mans - CHG

    Le Mans, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lille - CHU

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lyon - HCL

    Pierre-Bénite, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Marseille - APHM Nord

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Marseille - Hôpital Européen

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Montpellier - CHU

    Montpellier, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mulhouse - GHRMSA

    Mulhouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nantes - Hôpital Laennec

    Nantes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Nantes - Institut de Cancérologie de l'Ouest

    Saint-Herblain, 75009, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Paris - APHP Bichat

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Paris - APHP Cochin

    Paris, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Reims - Institut Godinot

    Reims, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Rennes - CHU

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Saint-Nazaire - Clinique Mutualiste de l'Estuaire

    Saint-Nazaire, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Strasbourg - Nouvel Hôpital Civil

    Strasbourg, 75009, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Toulon - CHI

    Toulon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Toulon - Sainte Anne HIA

    Toulon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Toulouse - CHU

    Toulouse, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Tours - CHU

    Tours, 75009, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vandoeuvre-lès-Nancy - Institut de Cancérologie de Lorraine

    Vandœuvre-lès-Nancy, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Villefranche sur Saône - CH

    Villefranche-sur-Saône, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Villejuif - Gustave Roussy

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••