Light therapy shows promise in tough mesothelioma trial
NCT ID NCT02662504
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tested whether adding intrapleural photodynamic therapy (PDT) to standard surgery and chemotherapy is safe and feasible for patients with malignant pleural mesothelioma. Six participants received a light-sensitive drug followed by laser light inside the chest cavity during surgery. The goal was to see if patients could complete the full treatment without severe side effects. Results will help decide if a larger trial comparing PDT to standard care is warranted.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
porfimer sodium (Photofrin) with laser light
What this could lead to
If successful, this could lead to a larger trial testing whether adding photodynamic therapy to standard surgery and chemotherapy improves survival for mesothelioma patients.
What could go wrong
This is a very small pilot study (6 participants) focused on feasibility and safety, not effectiveness. The treatment is complex and carries risks from surgery, chemotherapy, and light sensitivity. Results may not apply to all mesothelioma types.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MALIGNANT PLEURAL MESOTHELIOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
CHRU de Lille Hôpital Calmette
Lille, France